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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $89 | In Stock | |
5 mg | $239 | In Stock | |
10 mg | $378 | In Stock | |
25 mg | $628 | In Stock | |
50 mg | $886 | In Stock | |
100 mg | $1,190 | In Stock |
Description | Fz7-21 ((Ac)-LPSDDLEFWCHVMY-NH2) is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM). |
Targets&IC50 | FZD7 CRD (human):58 nM (EC50), FZD7 CRD (mouse):34 nM (EC50) |
Alias | (Ac)-LPSDDLEFWCHVMY-NH2 |
Molecular Weight | 1796.03 |
Formula | C83H114N18O23S2 |
Cas No. | 2247635-23-8 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 10 mM | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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