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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $41 | In Stock | |
50 mg | $135 | In Stock | |
100 mg | $203 | In Stock | |
1 mL x 10 mM (in DMSO) | $45 | In Stock |
Description | Bisdemethoxycurcumin (Curcumin III) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by macrophages (optimal stimulation at 100 nM BDMC) [1]. More stable than curcumin in physiological media, BDMC suppresses proliferation of cancer cells [2]. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits LPS induction of iNOS expression [3]. |
Alias | Curcumin III, Didemethoxycurcumin |
Molecular Weight | 308.33 |
Formula | C19H16O4 |
Cas No. | 24939-16-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMSO: 10 mg/mL Ethanol: 5 mg/mL |
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