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Nefopam hydrochloride

Nefopam hydrochloride
Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.
Catalog No. T0470Cas No. 23327-57-3
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Purity:99.97%
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Nefopam hydrochloride

Purity: 99.97%
Catalog No. T0470Alias Nefopam HCl, Fenazoxine hydrochlorideCas No. 23327-57-3

Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.
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500 mg$37In Stock
1 g$58In Stock
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Product Introduction

Bioactivity
Description
Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.
In vitro
The mechanism of action through which nefopam exerts its analgesic effects is, as of yet, largely unknown but may involve inhibition of serotonin, dopamine and noradrenaline reuptake.
AliasNefopam HCl, Fenazoxine hydrochloride
Chemical Properties
Molecular Weight289.8
FormulaC17H20ClNO
Cas No.23327-57-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 4.62 mg/mL (15.93 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4507 mL17.2533 mL34.5066 mL172.5328 mL
5 mM0.6901 mL3.4507 mL6.9013 mL34.5066 mL
10 mM0.3451 mL1.7253 mL3.4507 mL17.2533 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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