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PRI-724
Contact us for more batch information
PRI-724
Catalog No. T64414Cas No. 1422253-38-0
PRI-724 (C-82 prodrug) is a selective small-molecule inhibitor of β-catenin/CBP interaction.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $42 | In Stock | |
| 5 mg | $98 | In Stock | |
| 10 mg | $156 | In Stock | |
| 25 mg | $278 | In Stock | |
| 50 mg | $446 | In Stock | |
| 100 mg | $662 | In Stock |
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Questions
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CitedProduct Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | PRI-724 (C-82 prodrug) is a selective small-molecule inhibitor of β-catenin/CBP interaction. |
| In vivo | PRI-724 reduces liver fibrosis, and hepatic hydroxyproline levels, in HCV mice while attenuating αSMA induction. PRI-724 increased the levels of matrix metalloproteinase (MMP)-8 mRNA in the liver, along with elevated levels of intrahepatic neutrophils and macrophages/monocytes. In conclusion, PRI-724 ameliorates HCV-induced liver fibrosis in mice. PRI-724 is a drug candidate which possesses antifibrotic effect[1]. |
| Alias | C-82 prodrug, Foscenvivint |
| Molecular Weight | 658.64 |
| Formula | C33H35N6O7P |
| Cas No. | 1422253-38-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (83.51 mM)  Ethanol: 1.8 mg/mL (2.7 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
DMSO/Ethanol
DMSO
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