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fz7-21

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  • Inhibitors & Agonists
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Fz7-21
TP12632247635-23-8
Fz7-21 ((Ac)-LPSDDLEFWCHVMY-NH2) is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM).
  • $89
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CEF20 acetate(153045-21-7 free base)
TP1687L
CEF20 acetate is a CEF control peptide pool, is an HLA-A*0201-restricted epitope from cytomegalovirus pp65 (495-503).
  • $43
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Fz7-21 TFA (2247635-23-8 free base)
TP1262
Fz7-21 TFA ((Ac)-LPSDDLEFWCHVMY-NH2 TFA), a peptide antagonist of Frizzled 7 (FZD 7) receptors, selectively binds to FZD7 CRD subclass. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively.
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