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(1)
By Target- Wnt/beta-catenin
- Others(2)
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Results for "
intestinal organoids
" in TargetMol Product Catalog- Inhibitors & Agonists3
- Peptide Products1
Fz7-21
TP12632247635-23-8
Fz7-21 ((Ac)-LPSDDLEFWCHVMY-NH2) is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM).
- $41
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