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TAT-Gap19 acetate
Catalog No. TP2110L
TAT-Gap19 acetate is a specific inhibitor of connexin43 hemichannel (Cx43 HC). TAT-Gap19 acetate traverses the blood-brain barrier and alleviates liver fibrosis in mice. TAT-Gap19 acetate does not inhibit the corresponding Cx43 GJCs.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $97 | In Stock | |
| 5 mg | $197 | In Stock | |
| 10 mg | $338 | In Stock | |
| 25 mg | $597 | In Stock | |
| 50 mg | $852 | In Stock | |
| 100 mg | $1,170 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | TAT-Gap19 acetate is a specific inhibitor of connexin43 hemichannel (Cx43 HC). TAT-Gap19 acetate traverses the blood-brain barrier and alleviates liver fibrosis in mice. TAT-Gap19 acetate does not inhibit the corresponding Cx43 GJCs. |
| In vivo | TAT-Gap19 acetate (1 mg/kg/day) showed significantly decreased collagen deposition, as well as lower amounts of α-SMA-positive cells area in mice subjected to treatment with 100-200 mg thioacetamide (TAA)/kg body weight for eight weeks[1]. In 4 months old C57Bl6 male mice, TAT-Gap19 acetate (i.v.; 55 mg/kg) produces significant immune signal in the brain 24 h later[2]. |
| Molecular Weight | 2703.25 |
| Formula | C119H212N46O26 |
| Cas No. |
| Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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