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Description | α-Methyl-DL-aspartic acid serves as a specific inhibitor for the enzyme argininosuccinate synthase (ASS), which is the rate-limiting enzyme in the recycling pathway from 1-citrulline to 1-arginine [1]. |
In vitro | α-Methyl-dl-aspartic acid markedly diminishes the antihypertensive effects of Bj-BPP-10c in spontaneously hypertensive rats (SHR) [2]. |
In vivo | α-Methyl-dl-aspartic acid (147 mg/kg, i.v.) can attenuate l-citrulline-induced retinal vasodilation in Wistar rats [1]. |
Molecular Weight | 147.13 |
Formula | C5H9NO4 |
Cas No. | 2792-66-7 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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