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Peptide T acetate(106362-32-7 free base)

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Catalog No. TP1785L

Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a synthetic octapeptide whose possible mechanism of action is the competitive inhibition of gp120 to the CD4 receptor as well as binding to vasointestinal peptide receptors and inhibiting cytokine action

Peptide T acetate(106362-32-7 free base)

Peptide T acetate(106362-32-7 free base)

🥰Excellent
Purity: 99.47%
Catalog No. TP1785L
Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a synthetic octapeptide whose possible mechanism of action is the competitive inhibition of gp120 to the CD4 receptor as well as binding to vasointestinal peptide receptors and inhibiting cytokine action
Pack SizePriceAvailabilityQuantity
1 mg$58In Stock
5 mg$163In Stock
10 mg$275In Stock
25 mg$453In Stock
50 mg$636In Stock
100 mg$858In Stock
200 mg$1,150In Stock
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Purity:99.47%
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Product Introduction

Bioactivity
Description
Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a synthetic octapeptide whose possible mechanism of action is the competitive inhibition of gp120 to the CD4 receptor as well as binding to vasointestinal peptide receptors and inhibiting cytokine action
In vitro
Peptide T acts to block viral entry as it inhibits in the MAGI cell assay and blocks infection in the luciferase reporter assay using HIV virions pseudotyped with ADA envelope. Peptide T selectively inhibits HIV replication using chemokine receptor CCR5 compared to CXC4[2]. Peptide T at 10-8 M induces IL-10 production by the human Th2 cell line and PBMC. Also peptide T at 10-9 M concentration significantly inhibits IFN-g production by PBMC[3].
In vivo
Peptide T is administered subcutaneously at different doses and phases of the experimental autoimmune encephalomyelitis (EAE) disease, but Peptide T neither prevents nor ameliorates EAE[4].
Chemical Properties
Molecular Weight917.91
FormulaC37H59N9O18
SmilesC[C@H]([C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](C)N)O.CC(=O)O
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 5 mM
DMSO: Insoluble
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.0894 mL5.4472 mL10.8943 mL54.4716 mL
5 mM0.2179 mL1.0894 mL2.1789 mL10.8943 mL

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