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Pepstatin Ammonium

Name: Pepstatin Ammonium
Brand: TargetMol
SKU: T12407
Price: 28 EUR
Availability: InStock
Rating: 4.5 (1 reviews)

Catalog No. T12407

Alias Pepstatin A Ammonium

Pepstatin Ammonium is a specific inhibitor of aspartic proteaseproduced by actinomycetes(hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM , respectively). Pepstatin Ammonium also inhibits HIV protease.

Pepstatin Ammonium

Catalog No. T12407Alias Pepstatin A Ammonium

Product information is being updated, if you want to purchase, please click the bulk custom button.

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Questions

Resource Download

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Pepstatin Ammonium is a specific inhibitor of aspartic proteaseproduced by actinomycetes(hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM
Targets&IC50	Casein-proctase:290 nM , Hemoglobin-proctase:6.2 nM , Casein-pepsin:150 nM , Hemoglobin-pepsin:4.5 nM , Hemoglobin-acid protease:260 nM , Casein-acid protease:520 nM
In vitro	Pepstatin inhibits the recombinant HIV protease with an IC50 of 250 μM.
In vivo	Pepstatin suppresses stomach ulceration of the pylorus in ligated Shay rats[1].
Alias	Pepstatin A Ammonium

Chemical Properties

Molecular Weight	702.92
Formula	C₃₄H₆₆N₆O₉

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 41.67 mg/mL (59.28 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.4226 mL	7.1132 mL	14.2264 mL	71.1318 mL
5 mM	0.2845 mL	1.4226 mL	2.8453 mL	14.2264 mL
10 mM	0.1423 mL	0.7113 mL	1.4226 mL	7.1132 mL
20 mM	0.0711 mL	0.3557 mL	0.7113 mL	3.5566 mL
50 mM	0.0285 mL	0.1423 mL	0.2845 mL	1.4226 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Pepstatin Ammonium