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Eledoisin
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Catalog No. TP1177Cas No. 69-25-0
Alias Eledone peptide
Eledoisin (Eledone peptide) is an undecapeptide of mollusk origin in the tachykinin family of neuropeptides, serving as a specific agonist of NK2 and NK3 receptors.
Eledoisin
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Catalog No. TP1177Alias Eledone peptideCas No. 69-25-0
Eledoisin (Eledone peptide) is an undecapeptide of mollusk origin in the tachykinin family of neuropeptides, serving as a specific agonist of NK2 and NK3 receptors.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $215 | 35 days | |
| 5 mg | $840 | 35 days | |
| 10 mg | $1,470 | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Eledoisin (Eledone peptide) is an undecapeptide of mollusk origin in the tachykinin family of neuropeptides, serving as a specific agonist of NK2 and NK3 receptors. |
| In vitro | Eledoisin increases basal activity by 24.5±3.7%; however, its stimulation is significantly reduced to 13.1±1.9% in the presence of CP99994 (P<0.01). This effect demonstrates the compound's sensitivity to CP99994, further validated through similar tests with 0.1 μM SR48968 and 0.1 μM SB222200. SR48968 significantly decreases Eledoisin's effect (P<0.01), whereas SB222200 does not alter it. This data collectively indicates that Eledoisin's stimulatory action is diminished by CP99994 and SR48968, which are NK1 and NK2 antagonists, respectively[1]. |
| In vivo | Injection of Eledoisin (0.1-1 nmol/kg) into rats produces a biphasic cardiovascular response that consists of an initial fall of systemic blood pressure (8-15 mm Hg) followed by a rise (20-22 mm Hg). |
| Alias | Eledone peptide |
| Molecular Weight | 1188.4 |
| Formula | C54H85N13O15S |
| Cas No. | 69-25-0 |
| Relative Density. | 1.289 g/cm3 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | H2O: 18.15 mg/mL (15.27 mM), Sonication and heating are recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
H2O
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
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