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Neuromedin U-25 (human)
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Catalog No. TP2609Cas No. 312306-89-1
Neuromedin U-25 human, the active form of neuromedin U in humans, inhibits glucose-stimulated insulin secretion, leading to early-onset obesity, and serves as a vasoconstrictor in human vascular beds [1][2].
Neuromedin U-25 (human)
😃Good
Catalog No. TP2609Cas No. 312306-89-1
Neuromedin U-25 human, the active form of neuromedin U in humans, inhibits glucose-stimulated insulin secretion, leading to early-onset obesity, and serves as a vasoconstrictor in human vascular beds [1][2].
| Pack Size | Price | Availability | Quantity |
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| 10 mg | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Neuromedin U-25 human, the active form of neuromedin U in humans, inhibits glucose-stimulated insulin secretion, leading to early-onset obesity, and serves as a vasoconstrictor in human vascular beds [1][2]. |
| In vitro | Neuromedin U-25 human (4 pM-2 nM) binds to receptors in the human left ventricle and coronary artery, with K D values of 0.26 and 0.11 nM, respectively [1]. Additionally, Neuromedin U-25 human (0.1 nM-0.1 μM) induces endothelium-independent contraction in coronary, mammary, and saphenous vessels, with contraction potencies (pD 2) of 8.6, 8.0, and 8.2, respectively [1]. |
| Molecular Weight | 3080.37 |
| Formula | C141H203N41O38 |
| Cas No. | 312306-89-1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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