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COG-1410 acetate

COG-1410 acetate
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Purity:99.61%
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COG-1410 acetate

Catalog No. T30998L
COG-1410 acetate is an apolipoprotein E-derived peptide and can be used in studies about neurological diseases.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$113In Stock
5 mg$297In Stock
10 mg$497In Stock
25 mg$793In Stock
50 mg$1,130In Stock
100 mg$1,520In Stock
500 mg$2,970In Stock
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Product Introduction

Bioactivity
Description
COG-1410 acetate is an apolipoprotein E-derived peptide and can be used in studies about neurological diseases.
In vitro
In BV2 microglia cells, COG-1410 acetate (1-25 μM; 48 h) decreases the production and release of NO and TNFα[3].
In vivo
COG-1410 acetate (0.8 mg/kg; i.v.) improves vestibulomotor function, and decreases poststroke locomotor asymmetry, and infarct volume of the ipsilateral hemisphere in rats[1]. COG-1410 acetate (0.3-0.6 mg/kg; i.v.) exhibits significant improvement on a short-term test of vestibulomotor function and on a long-term test of spatial learning and memory in mice[3].
AliasCOG-1410 acetate(878009-24-6 Free base)
Chemical Properties
Molecular Weight1468.83
FormulaC66H125N21O16
Cas No.
Storage & Solubility Information
Storagekeep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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