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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $41 | In Stock | |
2 mg | $56 | In Stock | |
5 mg | $117 | In Stock | |
10 mg | $197 | In Stock | |
25 mg | $286 | In Stock | |
50 mg | $429 | In Stock | |
100 mg | $635 | In Stock | |
1 mL x 10 mM (in DMSO) | $297 | In Stock |
Description | Epidermal Growth Factor Receptor Peptide Acetate (Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)) exists on the cell surface and is activated by the binding of its specific ligands.EGFR belongs to the ErbB family of receptor tyrosine kinases (RTK). |
In vitro | This autophosphorylation elicits downstream activation and signaling by several other proteins that associate with the phosphorylated tyrosines through their own phosphotyrosine-binding SH2 domains.?These downstream signaling proteins initiate several signal transduction cascades, principally the MAPK, Akt and JNK pathways, which lead to DNA synthesis and cell proliferation.Such proteins modulate phenotypes such as cell migration, adhesion, and proliferation.?Activation of the receptor is important for the innate immune response in human skin.? |
Alias | EGF Receptor Peptide Acetate (96249-43-3 Free base), Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base) |
Molecular Weight | 1436.52 |
Formula | C63H97N13O25 |
Cas No. |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | H2O: 10 mg/mL (7.27mM) DMSO: 133mg/mL(96.62mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
DMSO/H2O
DMSO
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