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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $73 | In Stock | |
5 mg | $210 | In Stock | |
10 mg | $342 | In Stock | |
25 mg | $510 | In Stock | |
50 mg | $739 | In Stock | |
100 mg | $987 | In Stock | |
500 mg | $1,980 | In Stock |
Description | α-(difluoromethyl)-DL-Arginine (RMI 71897) is an enzyma-activated, irreversible inhibitor of arginine decarboxylase for E. coli (Ki = 800 μM), Pseudomonas aeruginosa, and Klebsiella pneumoniae. At 0.01 mM, it has been shown to prevent osmotic stress-induced increases in arginine decarboxylase activity and putrescine synthesis in oat leaf cells. When combined with a variety of polyamine analogues, α-(difluoromethyl)-DL-Arginine inhibited the growth of Trypanosoma Crui in mammalian host cells at a minimum concentration of 10 mM and prevented the growth of Trypanosoma Crui in T-cell receptor alpha-deficient mouse models. |
Alias | DFMA, RMI 71897, α-(difluoromethyl)-DL-Arginine |
Molecular Weight | 224.21 |
Formula | C7H14F2N4O2 |
Cas No. | 69955-43-7 |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||
Solubility Information | PBS (pH 7.2): 5 mg/mL PBS: 4.5 mg/mL (20.1 mM) | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
PBS
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