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[D-p-Cl-Phe6,Leu17]-VIP acetate

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TargetMol
Catalog No. TP2103L

[D-p-Cl-Phe6,Leu17]-VIP acetate is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor (IC50 = 125.8 nM).

[D-p-Cl-Phe6,Leu17]-VIP acetate

[D-p-Cl-Phe6,Leu17]-VIP acetate

🥰Excellent
TargetMol
Purity: 99.58%
Catalog No. TP2103L
[D-p-Cl-Phe6,Leu17]-VIP acetate is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor (IC50 = 125.8 nM).
Pack SizePriceAvailabilityQuantity
1 mg$243In Stock
5 mg$497In Stock
10 mg$857In Stock
25 mg$1,530In Stock
50 mg$2,310In Stock
100 mg$3,120In Stock
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Purity:99.58%
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Product Introduction

Bioactivity
Description
[D-p-Cl-Phe6,Leu17]-VIP acetate is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor (IC50 = 125.8 nM).
Targets&IC50
VIP receptor:125.8 nM
In vitro
[D-p-Cl-Phe6,Leu17]-VIP acetate is inactive at glucagon, secretin, and GRF receptors[1].
Chemical Properties
Molecular Weight3402.26
FormulaC150H243ClN44O44
Smiles[H]N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC(N)=O)=O)CC(C)C)=O)[C@H](CC)C)=O)CO)=O)CC(N)=O)=O)CC(C)C)=O)CC1=CC=C(C=C1)O)=O)CCCCN)=O)CCCCN)=O)C(C)C)=O)C)=O)CC(C)C)=O)CCC(N)=O)=O)CCCCN)=O)CCCNC(N)=N)=O)CC(C)C)=O)CCCNC(N)=N)=O)[C@H](O)C)=O)CC2=CC=C(C=C2)O)=O)CC(N)=O)=O)CC(O)=O)=O)[C@H](O)C)=O)CC3=CC=C(C=C3)Cl)=O)C(C)C)=O)C)=O)CC(O)=O)=O)CO)=O)CC4=CNC=N4.CC(O)=O
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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