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Description | Difelikefalin (CR-845; FE-202845) is a peripherally restricted, selective agonist of the kappa opioid receptor (KOR). It exhibits anti-inflammatory properties and holds promise for modulating pruritus in conditions associated with chronic kidney disease. |
In vitro | Difelikefalin (CR-845; FE-202845) is impermeable to the blood-brain barrier and specifically targets kappa opioid receptors (KORs), demonstrating no affinity for mu opioid receptors or any receptors other than KORs[1]. |
Alias | CR-845, FE-202845 |
Molecular Weight | 679.863 |
Formula | C36H53N7O6 |
Cas No. | 1024828-77-0 |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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