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Tiger17 TFA
Catalog No. T83744
Alias H-Trp-Cys-Lys-Pro-Lys-Pro-Lys-Pro-Arg-Cys-His-NH2
Tiger17, a cyclic peptide derivative of tigerinin-RC1 and tigerinin-RC2—antimicrobial peptides from the crab-eating frog (F. cancrivora) skin secretions—enhances HaCaT keratinocytes and human skin fibroblasts proliferation at 5 to 20 µg/ml concentrations, and promotes HaCaT cell migration at 20 µg/ml. Additionally, Tiger17 augments RAW 264.7 macrophages' recruitment and secretion of TGF-β1 and IL-6. When topically applied at 20 µg/ml, it accelerates wound closure and re-epithelialization in a mouse model of full-thickness dermal wounds.
Tiger17 TFA
Catalog No. T83744Alias H-Trp-Cys-Lys-Pro-Lys-Pro-Lys-Pro-Arg-Cys-His-NH2
Tiger17, a cyclic peptide derivative of tigerinin-RC1 and tigerinin-RC2—antimicrobial peptides from the crab-eating frog (F. cancrivora) skin secretions—enhances HaCaT keratinocytes and human skin fibroblasts proliferation at 5 to 20 µg/ml concentrations, and promotes HaCaT cell migration at 20 µg/ml. Additionally, Tiger17 augments RAW 264.7 macrophages' recruitment and secretion of TGF-β1 and IL-6. When topically applied at 20 µg/ml, it accelerates wound closure and re-epithelialization in a mouse model of full-thickness dermal wounds.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $63 | Backorder | |
| 5 mg | $235 | Backorder | |
| 10 mg | $437 | Backorder | |
| 25 mg | $932 | Backorder |
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Bioactivity
Chemical Properties
| Description | Tiger17, a cyclic peptide derivative of tigerinin-RC1 and tigerinin-RC2—antimicrobial peptides from the crab-eating frog (F. cancrivora) skin secretions—enhances HaCaT keratinocytes and human skin fibroblasts proliferation at 5 to 20 µg/ml concentrations, and promotes HaCaT cell migration at 20 µg/ml. Additionally, Tiger17 augments RAW 264.7 macrophages' recruitment and secretion of TGF-β1 and IL-6. When topically applied at 20 µg/ml, it accelerates wound closure and re-epithelialization in a mouse model of full-thickness dermal wounds. |
| Alias | H-Trp-Cys-Lys-Pro-Lys-Pro-Lys-Pro-Arg-Cys-His-NH2 |
| Molecular Weight | 1376.70 |
| Formula | C62H97N21O11S2.XCF3COOH |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O: Soluble |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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