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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | Brain Natriuretic Peptide-45, rat TFA (BNP-45, rat TFA) is an isoform of rat brain natriuretic peptide extracted from rat heart, exhibiting significant hypotensive and natriuretic effects [1]. |
In vivo | Brain Natriuretic Peptide-45, rat (BNP-45, 0.1-2.0 nmol/kg, i.v.) exhibits notable natriuretic and hypotensive effects in both anesthetized spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY). Higher concentrations of BNP-45 are more effective in reducing blood pressure in SHR. Compared to SHR, WKY rats demonstrate increased sensitivity to BNP-45's diuretic and natriuretic actions and enhanced urinary cGMP excretion. Additionally, elevated doses of BNP-45 result in sustained blood pressure reduction and urinary cGMP excretion in WKY [1]. |
Alias | BNP-45, rat TFA |
Cas No. |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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