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Tat-peptide 190-208 TFA

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Catalog No. T78040

Tat-peptide 190-208 TFA is a Tat-labeled, cell-permeable fusion peptide derived from residues 190-208 of rat G3BP1. The HIV-derived Tat sequence at the peptide's least conserved region confers cellular permeability. This compound promotes axon growth and enhances neurite formation per neuron, suggesting an axon intrinsic mechanism of action. Additionally, it has potential applications in providing ischemic protection during endovascular repair of intracranial aneurysms [1].

Tat-peptide 190-208 TFA

Tat-peptide 190-208 TFA

😃Good
Catalog No. T78040
Tat-peptide 190-208 TFA is a Tat-labeled, cell-permeable fusion peptide derived from residues 190-208 of rat G3BP1. The HIV-derived Tat sequence at the peptide's least conserved region confers cellular permeability. This compound promotes axon growth and enhances neurite formation per neuron, suggesting an axon intrinsic mechanism of action. Additionally, it has potential applications in providing ischemic protection during endovascular repair of intracranial aneurysms [1].
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Product Introduction

Bioactivity
Description
Tat-peptide 190-208 TFA is a Tat-labeled, cell-permeable fusion peptide derived from residues 190-208 of rat G3BP1. The HIV-derived Tat sequence at the peptide's least conserved region confers cellular permeability. This compound promotes axon growth and enhances neurite formation per neuron, suggesting an axon intrinsic mechanism of action. Additionally, it has potential applications in providing ischemic protection during endovascular repair of intracranial aneurysms [1].
In vitro
Tat-peptide 190-208 TFA at concentrations of 10 μM and 20 μM administered for 24 hours increased axonal length in isolated DRG cultures and the iMotor neurons, respectively [1]. Additionally, a 10 μM dose of Tat-peptide 190-208 TFA over a 3-day period increased the total number of axons extending from each neuron [1].
Chemical Properties
Molecular Weight3507.47
FormulaC142H214N40O57.C2HF3O2
Storage & Solubility Information
Storagekeep away from moisture | Shipping with blue ice.

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