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Lonodelestat TFA

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Catalog No. T76216

Lonodelestat TFA (POL6014 TFA) is a potent and selective peptide inhibitor of human neutrophil elastase (hNE) with demonstrated oral activity, showing promise for cystic fibrosis (CF) research [1] [2] [3].

Lonodelestat TFA
Other Forms of Lonodelestat TFA:
LonodelestatT41043906547-89-5
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Lonodelestat TFA

😃Good
Catalog No. T76216
Lonodelestat TFA (POL6014 TFA) is a potent and selective peptide inhibitor of human neutrophil elastase (hNE) with demonstrated oral activity, showing promise for cystic fibrosis (CF) research [1] [2] [3].
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Product Introduction

Bioactivity
Description
Lonodelestat TFA (POL6014 TFA) is a potent and selective peptide inhibitor of human neutrophil elastase (hNE) with demonstrated oral activity, showing promise for cystic fibrosis (CF) research [1] [2] [3].
Chemical Properties
Molecular Weight1592.75
FormulaC73H112F3N15O21
Storage & Solubility Information
Storagekeep away from moisture | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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