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Pep2-8 TFA

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Catalog No. T78013

Pep2-8 is a peptide that has demonstrated enhanced antagonistic activity against proprotein convertase subtilin/kexin type 9 (PCSK9) [1].

Pep2-8 TFA
Other Forms of Pep2-8 TFA:
Pep2-8TP18811541011-97-5
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Pep2-8 TFA

😃Good
Catalog No. T78013
Pep2-8 is a peptide that has demonstrated enhanced antagonistic activity against proprotein convertase subtilin/kexin type 9 (PCSK9) [1].
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Product Introduction

Bioactivity
Description
Pep2-8 is a peptide that has demonstrated enhanced antagonistic activity against proprotein convertase subtilin/kexin type 9 (PCSK9) [1].
In vitro
Pep2-8 TFA binds to the C-terminal truncated form of PCSK9 [1]. At a concentration of 50 μM, Pep2-8 TFA restores LDL uptake in PCSK9-processed HepG2 cells to approximately 90% of the control activity [1].
Chemical Properties
Molecular Weight1715.85 (free base)
FormulaC85H111F3N16O26
Storage & Solubility Information
Storagekeep away from moisture | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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