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[(pF)Phe4]Nociceptin(1-13)NH2 acetate
🥰Excellent
Catalog No. TP1885L1
[(pF)Phe4]Nociceptin(1-13)NH2 acetate is a selective agonist of NOP receptor with a pKi of 10.68 and a pEC50 of 9.31. [(pF)Phe4]Nociceptin(1-13)NH2 acetate displays high selectivity over δ, κ, and μ opioid receptors (>3000 fold).
![[(pF)Phe4]Nociceptin(1-13)NH2 acetate](/group3/M00/02/51/CgoaEGY7L6yERcQNAAAAAC-FzcM179.png)
[(pF)Phe4]Nociceptin(1-13)NH2 acetate
🥰Excellent
Purity: 98.03%
Catalog No. TP1885L1
[(pF)Phe4]Nociceptin(1-13)NH2 acetate is a selective agonist of NOP receptor with a pKi of 10.68 and a pEC50 of 9.31. [(pF)Phe4]Nociceptin(1-13)NH2 acetate displays high selectivity over δ, κ, and μ opioid receptors (>3000 fold).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $327 | In Stock | |
| 2 mg | $492 | In Stock | |
| 5 mg | $737 | In Stock | |
| 10 mg | $1,110 | In Stock | |
| 25 mg | $1,650 | In Stock | |
| 50 mg | $2,230 | In Stock | |
| 100 mg | $2,930 | In Stock |
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Purity:98.03%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | [(pF)Phe4]Nociceptin(1-13)NH2 acetate is a selective agonist of NOP receptor with a pKi of 10.68 and a pEC50 of 9.31. [(pF)Phe4]Nociceptin(1-13)NH2 acetate displays high selectivity over δ, κ, and μ opioid receptors (>3000 fold). |
| In vivo | In unanaesthetised normotensive mice, [(pF)Phe4]Nociceptin(1-13)NH2 acetate (100 nmol/kg; i.c.v.) dose-dependently stimulated feeding in rats and is about tenfold more potent than NC(1-13)NH2. [(pF)Phe4]Nociceptin(1-13)NH2 acetate (100 nmol/kg; i.v.) decreases mean blood pressure and heart rate; these effects are longer lasting than those elicited by the same dose of NC(1-13)NH2[1]. |
| Molecular Weight | 1459.63 |
| Formula | C63H103FN22O17 |
| Smiles | CC(O)=O.O=C([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H](CO)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](C)NC(CNC([C@H]([C@@H](C)O)NC([C@H](CC(C=C1)=CC=C1F)NC(CNC(CNC([C@H](CC2=CC=CC=C2)N)=O)=O)=O)=O)=O)=O)=O)=O)CCCCN)=O)=O)=O)=O)CCCCN)N |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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