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MMK 1 acetate
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Catalog No. TP1891L1
Alias MMK 1 acetate(271246-66-3 free base)
MMK 1 acetate is an agonist of formyl peptide receptor 2 (FPR2), which was previously known as formyl peptide receptor-like 1 (FPRL1) [1].
MMK 1 acetate
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Purity: 99.11%
Catalog No. TP1891L1Alias MMK 1 acetate(271246-66-3 free base)
MMK 1 acetate is an agonist of formyl peptide receptor 2 (FPR2), which was previously known as formyl peptide receptor-like 1 (FPRL1) [1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $118 | In Stock | |
| 5 mg | $266 | In Stock | |
| 10 mg | $393 | In Stock | |
| 25 mg | $592 | In Stock | |
| 50 mg | $833 | In Stock | |
| 100 mg | $1,120 | In Stock | |
| 200 mg | $1,520 | In Stock |
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Purity:99.11%
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Product Introduction
Bioactivity
Chemical Properties
| Description | MMK 1 acetate is an agonist of formyl peptide receptor 2 (FPR2), which was previously known as formyl peptide receptor-like 1 (FPRL1) [1]. |
| In vitro | MMK1 induced calcium flux in CHO cells expressing human FPR2 and Gα16 (EC50 = <2 nM) but not in CHO cells expressing Gα16 alone or in combination with FPR1 (EC50s = >10,000 nM for both). It induced chemotaxis of isolated human peripheral blood monocytes and neutrophils in a concentration-dependent manner [2]. MMK1 (10 µM) increases production of the proinflammatory cytokines IL-1β and IL-6 in isolated human monocytes [3]. |
| In vivo | Intracerebroventricular administration of MMK1 (100 pmol/mouse) increases the percentage of time spent in the open arms of the elevated plus maze in mice, indicating anxiolytic-like activity [3]. |
| Alias | MMK 1 acetate(271246-66-3 free base) |
| Molecular Weight | 1671.01 |
| Formula | C77H127N19O20S |
| Smiles | O=C(O)[C@@H](NC([C@H](NC([C@H](NC([C@@H](NC([C@H](NC([C@H](NC([C@H](NC([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)NC([C@H](N)CC(C)C)=O)=O)CO)=O)[C@@H](C)CC)=O)CC1=CC=CC=C1)=O)CCCNC(N)=N)=O)CO)=O)CC(C)C)=O)CC(C)C)=O)CC2=CC=CC=C2)=O)CCCNC(N)=N)=O)C(C)C)=O)CCSC.CC(O)=O |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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