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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $266 | In Stock | |
5 mg | $698 | In Stock | |
10 mg | $993 | In Stock | |
25 mg | $1,470 | In Stock | |
50 mg | $1,990 | In Stock | |
100 mg | $2,680 | In Stock |
Description | Tirzepatide (LY-3298176) is a dual agonist of glucose-dependent polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor with neuroprotective activity for the study of diabetes and obesity. |
In vitro | In SHSY5Y cells, treatment with Tirzepatide (0-0.4 μM; 7 days) upregulated the mRNA expression and protein levels of both CREB and BDNF, while increasing the protein levels of Bcl-2, pAkt, MAP2, GAP43, AGBL4, GLUT4, and SORBS1[1]. |
In vivo | In diet-induced obese (DIO) mice, treatment with Tirzepatide (10 nM/kg; subcutaneous injection) resulted in reduced body weight and food consumption, as well as decreased levels of glucose, insulin, leptin, and C-peptide[2]. |
Alias | LY-3298176 |
Molecular Weight | 4813.45 |
Formula | C225H348N48O68 |
Cas No. | 2023788-19-2 |
Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (20.78 mM) ![]() | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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