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CGRP (83-119), rat TFA (Calcitonin Gene Related Peptide(83-119), rat TFA) is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $181 | In Stock | |
5 mg | $442 | In Stock | |
10 mg | $592 | In Stock | |
25 mg | $918 | In Stock | |
50 mg | $1,180 | In Stock | |
100 mg | $1,670 | In Stock | |
200 mg | $2,250 | In Stock |
Description | CGRP (83-119), rat TFA (Calcitonin Gene Related Peptide(83-119), rat TFA) is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor. |
In vitro | Calcitonin Gene Related Peptide (CGRP) (83-119), rat (TFA) belongs to the calcitonin family of neuropeptides which also includes adrenomedullin, amylin, calcitonin, intermedin and calcitonin receptor-stimulating peptide. Calcitonin Gene Related Peptide (CGRP) has two isoforms (αCGRP and βCGRP), and acts through calcitonin receptor-like receptor (CRLR)[1]. Calcitonin Gene Related Peptide (CGRP) plays a key role in migraine pathophysiology and is associated with activation of the trigeminovascular system. CGRP prossibly acts postjunctionally in these areas putatively involved in primary headaches[2]. |
In vivo | Calcitonin Gene Related Peptide (CGRP) (83-119), rat (TFA) is a potent inducer of oedema in rat orofacial tissue. CGRP (100 μL; 8-33 pM) induces a rapidly developing (5-15?min) and long-lasting (6?h), dose-dependent oedema in the rat cheek. CGRP induces a smaller oedematogenic effect in the rat hind paw also blocked by the CGRP antagonist. CGRP (16 pM) potentiates the oedema induced by co-injected substance P (3.7 nM)[3]. |
Alias | Calcitonin Gene Related Peptide(83-119), rat TFA |
Molecular Weight | 3920.32 |
Formula | C162H262N50O52S2.C2HF3O2 |
Relative Density. | no data available |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
Solubility Information | H2O: 10 mg/mL (2.55 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
H2O
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