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TfR-T12 acetate

🥰Excellent
Catalog No. T40428L
Alias TfR-T12 acetate (344618-30-0 Free base)

TfR-T12 acetate is a peptide binding to the transferrin receptor (TfR) and is subsequently internalized into TfR-expressing cells.

TfR-T12 acetate
Other Forms of TfR-T12 acetate:

TfR-T12 acetate

🥰Excellent
Purity: 97%
Catalog No. T40428LAlias TfR-T12 acetate (344618-30-0 Free base)
TfR-T12 acetate is a peptide binding to the transferrin receptor (TfR) and is subsequently internalized into TfR-expressing cells.
Pack SizePriceAvailabilityQuantity
1 mg$87In Stock
5 mg$176In Stock
10 mg$293In Stock
25 mg$527In Stock
50 mg$762In Stock
100 mg$1,070In Stock
500 mg$2,130In Stock
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Purity:97%
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Product Introduction

Bioactivity
Description
TfR-T12 acetate is a peptide binding to the transferrin receptor (TfR) and is subsequently internalized into TfR-expressing cells.
In vitro
TfR-T12 acetate can be chemically conjugated with a pegylated lipid derivative, 3-(N-succinimidyloxyglutaryl)aminopropyl- polyethyleneglycol(2000)- carbamyl distearoyl phosphatidylethanolamine (NHS-PEG2000-DSPE), and used as a functional material to construct the multifunctional lipid vesicles[1].
In vivo
In brain glioma-bearing mice, TfR-T12 acetate is transported across the BBB, killing brain glioma and glioma stem cells via the induction of necrosis, apoptosis and autophagy[2].
AliasTfR-T12 acetate (344618-30-0 Free base)
Chemical Properties
Molecular Weight1550.78
FormulaC73H103N19O17S
SmilesC[C@@H](O)[C@@H](C(N[C@@H](CC1=CN=CN1)C(N[C@@H](CCCNC(N)=N)C(N2CCC[C@H]2C(N3CCC[C@H]3C(N[C@H](C(N[C@@H](CC4=CNC5=CC=CC=C45)C(N[C@H](C(N6CCC[C@H]6C(N[C@H](C(N[C@H](C(N7[C@@H](CCC7)C(O)=O)=O)CC8=CNC9=CC=CC=C98)=O)C(C)C)=O)=O)CO)=O)=O)CCSC)=O)=O)=O)=O)=O)N.CC(O)=O
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

transferrin receptorTfR-T12 AcetateTfRT12 acetateTfR T12 acetate344618-30-0 Free base344618-30-0
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