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TAT-P4-(DATC5)2 is a potent peptide inhibitor of the PDZ domain of protein interacting with C kinase-1 (PICK1), with a high affinity dissociation constant (K_i) of 1.7 nM. This compound has demonstrated the ability to mitigate addiction behaviors in rat models [1].
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50 mg | Inquiry | Backorder |
Description | TAT-P4-(DATC5)2 is a potent peptide inhibitor of the PDZ domain of protein interacting with C kinase-1 (PICK1), with a high affinity dissociation constant (K_i) of 1.7 nM. This compound has demonstrated the ability to mitigate addiction behaviors in rat models [1]. |
In vivo | TAT-P4-(DATC5)2, administered intravenously at concentrations of 0.99 μg/kg and 9.9 μg/kg, dose-dependently attenuates the reinstatement of drug-seeking behavior in rats without inducing operational learning deficits or suppressing motor activity [1]. |
Storage | keep away from moisture | Shipping with blue ice. |
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