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MOTS-c(Human) Acetate（1627580-64-6 free）
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MOTS-c(Human) Acetate（1627580-64-6 free）
Catalog No. TP2312
MOTS-c(Human) Acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c(human) acetate induces glucose uptake and improves insulin sensitivity. MOTS-c(human) acetate has implications in the regulation of obesity, diabetes, exercise, and longevity.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $90 | In Stock | |
| 5 mg | $170 | In Stock | |
| 10 mg | $243 | In Stock | |
| 25 mg | $437 | In Stock | |
| 50 mg | $607 | In Stock | |
| 100 mg | $863 | In Stock | |
| 500 mg | $1,760 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | MOTS-c(Human) Acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c(human) acetate induces glucose uptake and improves insulin sensitivity. MOTS-c(human) acetate has implications in the regulation of obesity, diabetes, exercise, and longevity. |
| In vitro | MOTS-c inhibits the folate cycle at the level of 5Me-THF, resulting in an accumulation of AICAR [5-aminoimidazole-4-carboxamide ribonucleotide). MOTS-c also increases cellular NAD+ levels, which are also nucleotide precursors[1]. |
| In vivo | MOTS-c injections in mice show activation of skeletal muscle AMPK and increased the level of its downstream glucose transporter GLUT4. MOTS-c may also act as a potential mitochondrial signal that mediates an exercise-induced mitohormesis response, thereby stimulating physiological adaptation and increased tolerance to exercise[1]. |
| Molecular Weight | 2234.64 |
| Formula | C103H156N28O24S2 |
| Cas No. |
| Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||
| Solubility Information | DMSO: 10 mM | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
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