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Methyl cinnamate

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Purity:99.95%

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COA HNMR HPLC

Methyl cinnamate

Catalog No. T5552Cas No. 103-26-4

Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.

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Pack Size	Price	Availability	Quantity
5 g	$44	In Stock
10 g	$63	In Stock

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Product Introduction

Bioactivity

Description

Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.

In vitro

At 1-3000 μmol/L, the E-isomer of methyl cinnamate (E-MC) concentration-dependently relaxed endothelium-intact aortic preparations that had been precontracted with phenylephrine (PHE; 1 μmol/L), with an IC50 value (geometric mean) of 877.6 μmol/L (95% confidence interval (CI) 784.1-982.2 μmol/L). Over the concentration range 1-3000 μmol/L, E-MC relaxed K(+) -induced contractions in mesenteric artery preparations (IC50 314.5 μmol/L; 95% CI 141.9-697.0 μmol/L) with greater potency than in aortic preparations (IC50 1144.7 μmol/L; 95% CI 823.2-1591.9 μmol/L).

Chemical Properties

Molecular Weight	162.19
Formula	C10H10O2
Cas No.	103-26-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: Insoluble

DMSO: 50 mg/mL (308.28 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.1656 mL	30.8280 mL	61.6561 mL	308.2804 mL
5 mM	1.2331 mL	6.1656 mL	12.3312 mL	61.6561 mL
10 mM	0.6166 mL	3.0828 mL	6.1656 mL	30.8280 mL
20 mM	0.3083 mL	1.5414 mL	3.0828 mL	15.4140 mL
50 mM	0.1233 mL	0.6166 mL	1.2331 mL	6.1656 mL
100 mM	0.0617 mL	0.3083 mL	0.6166 mL	3.0828 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

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