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KRFK TFA

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Catalog No. T78544

KRFK TFA, a TSP-1-derived peptide, activates TGF-β and enhances its associated signaling pathways independently of thrombospondin (TSP) receptors like CD47 and CD36. This compound has potential applications in research on chronic ocular surface inflammatory disorders [1].

KRFK TFA

KRFK TFA

🥰Excellent
Catalog No. T78544
KRFK TFA, a TSP-1-derived peptide, activates TGF-β and enhances its associated signaling pathways independently of thrombospondin (TSP) receptors like CD47 and CD36. This compound has potential applications in research on chronic ocular surface inflammatory disorders [1].
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Product Introduction

Bioactivity
Description
KRFK TFA, a TSP-1-derived peptide, activates TGF-β and enhances its associated signaling pathways independently of thrombospondin (TSP) receptors like CD47 and CD36. This compound has potential applications in research on chronic ocular surface inflammatory disorders [1].
In vitro
KRFK TFA (50 μM; 24 h) stimulates TGF-β secretion and decreases dendritic cell maturation markers in TSP-1-deficient bone marrow-derived dendritic cells (BMDCs) [1].
In vivo
KRFK TFA (administered as a single dose of 5 μg/5 µL to one eye) significantly prevented the development of chronic ocular surface inflammation in TSP-1 -/- mice [1].
Chemical Properties
FormulaC27H47N9O5.xC2HF3O2
Storage & Solubility Information
Storagekeep away from moisture | Shipping with blue ice.

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