Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

β-Amyloid (1-40), FAM-labeled

😃Good
Catalog No. T39146Cas No. 1678416-08-4

β-Amyloid (1-40), FAM-labeled, is a β-Amyloid (1-40) peptide tagged with a FAM fluorescent label, exhibiting an excitation wavelength (λ ex) of 492 nm and an emission wavelength (λ em) of 518 nm.

β-Amyloid (1-40), FAM-labeled

β-Amyloid (1-40), FAM-labeled

😃Good
Catalog No. T39146Cas No. 1678416-08-4
β-Amyloid (1-40), FAM-labeled, is a β-Amyloid (1-40) peptide tagged with a FAM fluorescent label, exhibiting an excitation wavelength (λ ex) of 492 nm and an emission wavelength (λ em) of 518 nm.
Pack SizePriceAvailabilityQuantity
100 mgInquiryBackorder
500 mgInquiryBackorder
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
β-Amyloid (1-40), FAM-labeled, is a β-Amyloid (1-40) peptide tagged with a FAM fluorescent label, exhibiting an excitation wavelength (λ ex) of 492 nm and an emission wavelength (λ em) of 518 nm.
In vitro
The transport of fluorescently labeled Aβ42, both FAM-labeled and Fluor 488-labeled Human β-Amyloid (1-42), as well as scrambled Aβ42 (FAM-labeled scrambled β-Amyloid (1-42)), across an endothelial monolayer, is analyzed in an in vitro blood-brain barrier (BBB) model, utilizing transendothelial electrical resistance (TEER) to monitor changes over time (specifically over 120 minutes, with or without the presence of Aβ24). It's observed that the presence of Human β-Amyloid (1-24) at a concentration of 1 μM results in the retention of H-Aβ42, which impairs its efflux from the BBB, thus hindering the molecule's effective clearance. When FAM-labeled or Fluor 488-conjugated H-Aβ42 is applied to the apical side of the cell inserts, it demonstrates successful cross-BBB migration, unlike the FAM-labeled scrambled β-Amyloid (1-42), which does not efficiently cross.
Chemical Properties
Cas No.1678416-08-4
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy β-Amyloid (1-40), FAM-labeled | purchase β-Amyloid (1-40), FAM-labeled | β-Amyloid (1-40), FAM-labeled cost | order β-Amyloid (1-40), FAM-labeled | β-Amyloid (1-40), FAM-labeled chemical structure | β-Amyloid (1-40), FAM-labeled in vitro