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[Sar9,Met(O2)11]-Substance P acetate
🥰Excellent
Catalog No. TP1369L
Alias [Sar9,Met(O2)11]-Substance P acetate(110880-55-2 free base)
[Sar9,Met(O2)11]-Substance P acetate is a tachykinin NK1 receptor selective agonist. [Sar9,Met(O2)11]-Substance P acetate is a selective tachykinin NK1 receptor agonist.[Sar9,Met(O2)11]-Substance P acetate and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P acetate is the sole to produce grooming.
![[Sar9,Met(O2)11]-Substance P acetate](/group3/M00/3F/91/CgoaEWfhCvyEVBTOAAAAAMbRNpc561.png)
[Sar9,Met(O2)11]-Substance P acetate
🥰Excellent
Purity: 100%
Catalog No. TP1369LAlias [Sar9,Met(O2)11]-Substance P acetate(110880-55-2 free base)
[Sar9,Met(O2)11]-Substance P acetate is a tachykinin NK1 receptor selective agonist. [Sar9,Met(O2)11]-Substance P acetate is a selective tachykinin NK1 receptor agonist.[Sar9,Met(O2)11]-Substance P acetate and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P acetate is the sole to produce grooming.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $92 | In Stock | |
| 5 mg | $367 | In Stock | |
| 10 mg | $546 | In Stock | |
| 25 mg | $879 | In Stock | |
| 50 mg | $1,190 | In Stock | |
| 100 mg | $1,630 | In Stock | |
| 500 mg | $3,260 | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | [Sar9,Met(O2)11]-Substance P acetate is a tachykinin NK1 receptor selective agonist. [Sar9,Met(O2)11]-Substance P acetate is a selective tachykinin NK1 receptor agonist.[Sar9,Met(O2)11]-Substance P acetate and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P acetate is the sole to produce grooming. |
| In vitro | [Sar9,Met(O2)11]-Substance P and septide (10-100?pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P is the sole to produce grooming[1]. |
| Alias | [Sar9,Met(O2)11]-Substance P acetate(110880-55-2 free base) |
| Molecular Weight | 1471.75 |
| Formula | C66H106N18O18S |
| Smiles | O=C(N1CCC[C@H]1C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N(CC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCS(C)(=O)=O)=O)=O)C)=O)=O)CC3=CC=CC=C3)=O)=O)CCC(N)=O)=O)[C@H](CCCCN)NC([C@H]4N(CCC4)C([C@H](CCCNC(N)=N)N)=O)=O.CC(O)=O.O |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 10 mM, Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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