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Lanreotide acetate (BIM 23014 acetate) is a somatostatin analogue with antineoplastic activity, used for carcinoid syndrome
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $37 | In Stock | |
5 mg | $59 | In Stock | |
10 mg | $97 | In Stock | |
25 mg | $176 | In Stock | |
50 mg | $262 | In Stock | |
100 mg | $389 | In Stock | |
1 mL x 10 mM (in DMSO) | $133 | In Stock |
Description | Lanreotide acetate (BIM 23014 acetate) is a somatostatin analogue with antineoplastic activity, used for carcinoid syndrome |
In vivo | In a mouse GH3 tumor xenograft model, lanreotide 10 mg/kg moderately inhibited the growth of GH3 tumors, with a 4x tumor growth delay (TGD) time that ranged from 4.5 to 8.3 days. Fractionated local tumor radiation alone significantly inhibited tumor growth and produced a TGD of 35.1+/-5.7 days for 250 cGy fractions[1]. |
Animal Research | Animal Model:Male nude mice, 8 weeks old and 20–25?g in body weight (GH3 tumor-bearing nude mice).Dosage: 2.5, 5, 10?mg/kg. Administration:Subcutaneous; daily for 5 days[1] |
Alias | Lanreotide acetate (108736-35-2 free base), BIM 23014 acetate, BIM 23014 (acetate) |
Molecular Weight | 1156.39 |
Formula | C56H73N11O12S2 |
Cas No. | 2378114-72-6 |
Smiles | CC(O)=O.[H][C@@]1(CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@]([H])(CSSC[C@H](NC(=O)[C@@H](NC1=O)C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@H](N)Cc1ccc2ccccc2c1 |
Relative Density. | no data available |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 22.5 mg/mL (19.46 mM) | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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