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Lanreotide acetate

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Catalog No. T8359Cas No. 2378114-72-6
Alias Lanreotide acetate (108736-35-2 free base), BIM 23014 acetate, BIM 23014 (acetate)

Lanreotide acetate (BIM 23014 acetate) is a somatostatin analogue with antineoplastic activity, used for carcinoid syndrome

Lanreotide acetate

Lanreotide acetate

🥰Excellent
Purity: 100%
Catalog No. T8359Alias Lanreotide acetate (108736-35-2 free base), BIM 23014 acetate, BIM 23014 (acetate)Cas No. 2378114-72-6
Lanreotide acetate (BIM 23014 acetate) is a somatostatin analogue with antineoplastic activity, used for carcinoid syndrome
Pack SizePriceAvailabilityQuantity
2 mg$37In Stock
5 mg$59In Stock
10 mg$97In Stock
25 mg$176In Stock
50 mg$262In Stock
100 mg$389In Stock
1 mL x 10 mM (in DMSO)$133In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Lanreotide acetate (BIM 23014 acetate) is a somatostatin analogue with antineoplastic activity, used for carcinoid syndrome
In vivo
In a mouse GH3 tumor xenograft model, lanreotide 10 mg/kg moderately inhibited the growth of GH3 tumors, with a 4x tumor growth delay (TGD) time that ranged from 4.5 to 8.3 days. Fractionated local tumor radiation alone significantly inhibited tumor growth and produced a TGD of 35.1+/-5.7 days for 250 cGy fractions[1].
Animal Research
Animal Model:Male nude mice, 8 weeks old and 20–25?g in body weight (GH3 tumor-bearing nude mice).Dosage: 2.5, 5, 10?mg/kg. Administration:Subcutaneous; daily for 5 days[1]
AliasLanreotide acetate (108736-35-2 free base), BIM 23014 acetate, BIM 23014 (acetate)
Chemical Properties
Molecular Weight1156.39
FormulaC56H73N11O12S2
Cas No.2378114-72-6
SmilesCC(O)=O.[H][C@@]1(CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@]([H])(CSSC[C@H](NC(=O)[C@@H](NC1=O)C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)NC(=O)[C@H](N)Cc1ccc2ccccc2c1
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 22.5 mg/mL (19.46 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.8648 mL4.3238 mL8.6476 mL43.2380 mL
5 mM0.1730 mL0.8648 mL1.7295 mL8.6476 mL
10 mM0.0865 mL0.4324 mL0.8648 mL4.3238 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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