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Speract

Catalog No. T7487Cas No. 76901-59-2

Speract, a peptide from sea urchin eggs, regulates sperm motility and stimulates sperm mitochondrial metabolism.

Speract

Speract

Catalog No. T7487Cas No. 76901-59-2
Speract, a peptide from sea urchin eggs, regulates sperm motility and stimulates sperm mitochondrial metabolism.
Pack SizePriceAvailabilityQuantity
1 mg$70Backorder
5 mg$246Backorder
10 mg$442Backorder
25 mg$796Backorder
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Product Introduction

Bioactivity
Description
Speract, a peptide from sea urchin eggs, regulates sperm motility and stimulates sperm mitochondrial metabolism.
In vitro
The stimulation of sperm with speract depolarizes the mitochondrion and increases the levels of NADH.?Surprisingly, these responses are independent of external Ca(2+) and are due to the increase in intracellular pH (pHi) induced by speract.?Speract, by regulating pHi, in addition to [Ca(2+)]i, may finely modulate mitochondrial metabolism to control motility and ensure that sperm reach the egg and fertilize it[1].
Chemical Properties
Molecular Weight891.93
FormulaC38H57N11O14
Cas No.76901-59-2
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 10 mM
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.1212 mL5.6058 mL11.2116 mL56.0582 mL
5 mM0.2242 mL1.1212 mL2.2423 mL11.2116 mL
10 mM0.1121 mL0.5606 mL1.1212 mL5.6058 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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