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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $48 | In Stock | |
10 mg | $58 | In Stock | |
50 mg | $67 | In Stock | |
100 mg | $108 | In Stock |
Description | Argireline (Acetyl hexapeptide-3) is composed of chains of amino acids known as peptides. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline has antiwrinkle and anti-aging activity[1][2][3]. |
In vitro | The incubation of Argireline solution in different concentrations with human embryonic kidney HEK-293 (IC50 of 34.862 μM) and neuroblastoma IMR-32 cells (IC50 of 68.458 μM)) for 48 h have dose dependent antiproliferative effect. Argireline solution incubated in different concentrations with HSF has a dose-dependent antiproliferative effect on those cells. Argireline in low concentration do not affect cell proliferation[2]. |
In vivo | Argireline was administered topically to elderly mice twice daily for six weeks, resulting in notable histological improvements in skin tissue. Specifically, the quantity of type I collagen fibers increased significantly (P < 0.01), and the amount of type III collagen fibers decreased (P < 0.05). This demonstrates Argireline's capability to enhance the histological architecture of skin tissue and restore aged skin[3]. |
Alias | Acetyl hexapeptide-3 |
Molecular Weight | 888.99 |
Formula | C34H60N14O12S |
Cas No. | 616204-22-9 |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||
Solubility Information | DMSO: 10mM | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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