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PTPσ Inhibitor, ISP
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Catalog No. T80544
PTPσ Inhibitor ISP is a compound that binds to recombinant human PTPs, thereby inhibiting PTPσ signaling. It has the capability to penetrate membranes and counteract the inhibitory effects of chondroitin sulfate proteoglycan (CSPG) on axonal sprouting in spinal cord injury models. Additionally, it fosters remyelination in lysolecithin (LPC)-induced demyelinated spinal cords and supports the migration and maturation of oligodendrocyte progenitor cells (OPCs), enhancing remyelination and functional recovery in Multiple Sclerosis (MS) animal models [1] [2].
PTPσ Inhibitor, ISP
PTPσ Inhibitor, ISP
😃Good
Catalog No. T80544
PTPσ Inhibitor ISP is a compound that binds to recombinant human PTPs, thereby inhibiting PTPσ signaling. It has the capability to penetrate membranes and counteract the inhibitory effects of chondroitin sulfate proteoglycan (CSPG) on axonal sprouting in spinal cord injury models. Additionally, it fosters remyelination in lysolecithin (LPC)-induced demyelinated spinal cords and supports the migration and maturation of oligodendrocyte progenitor cells (OPCs), enhancing remyelination and functional recovery in Multiple Sclerosis (MS) animal models [1] [2].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | PTPσ Inhibitor ISP is a compound that binds to recombinant human PTPs, thereby inhibiting PTPσ signaling. It has the capability to penetrate membranes and counteract the inhibitory effects of chondroitin sulfate proteoglycan (CSPG) on axonal sprouting in spinal cord injury models. Additionally, it fosters remyelination in lysolecithin (LPC)-induced demyelinated spinal cords and supports the migration and maturation of oligodendrocyte progenitor cells (OPCs), enhancing remyelination and functional recovery in Multiple Sclerosis (MS) animal models [1] [2]. |
| Molecular Weight | 4318.93 |
| Formula | C177H306N66O54S3 |
Storage & Solubility Information
| Storage | keep away from moisture | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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