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Neuropeptide Y (human) (TFA)
Catalog No. T36446
Neuropeptide Y (human) TFA, a compound implicated in Alzheimer's disease (AD), exhibits protective effects against β-Amyloid toxicity in rat cortical neurons.
Neuropeptide Y (human) (TFA)
Neuropeptide Y (human) (TFA)
Catalog No. T36446
Neuropeptide Y (human) TFA, a compound implicated in Alzheimer's disease (AD), exhibits protective effects against β-Amyloid toxicity in rat cortical neurons.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $148 | Backorder | |
| 5 mg | $598 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Neuropeptide Y (human) TFA, a compound implicated in Alzheimer's disease (AD), exhibits protective effects against β-Amyloid toxicity in rat cortical neurons. |
| In vitro | Neuropeptide Y (human) has been shown to shield cortical neurons from the toxicity of Aβ25-35. At concentrations of 2 μM, it counteracts the harmful effects of Aβ25-35 at both 24 and 48 hours. This protective impact on neuronal survival is consistent across neurons pre-exposed to 1 μM and 0.5 μM Neuropeptide Y (human) treatments. Furthermore, pretreatment with Neuropeptide Y (29-64), amide, human (TFA), enhances NGF synthesis and release while reducing NGF mRNA levels in cortical neurons challenged with Aβ35-25[1]. |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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