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Ac-Leu-Arg-AMC

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Catalog No. TP1368Cas No. 929621-79-4

Ac-Leu-Arg-AMC (Acetyl-Leucyl-Arginyl-7-amido-4-methylcoumarin) is a fluorogenic peptide substrate.

Ac-Leu-Arg-AMC

Ac-Leu-Arg-AMC

😃Good
Catalog No. TP1368Cas No. 929621-79-4
Ac-Leu-Arg-AMC (Acetyl-Leucyl-Arginyl-7-amido-4-methylcoumarin) is a fluorogenic peptide substrate.
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Product Introduction

Bioactivity
Description
Ac-Leu-Arg-AMC (Acetyl-Leucyl-Arginyl-7-amido-4-methylcoumarin) is a fluorogenic peptide substrate.
Chemical Properties
Molecular Weight486.56
FormulaC24H34N6O5
Cas No.929621-79-4
Relative Density.1.32 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 300 mg/mL (616.57 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0552 mL10.2762 mL20.5524 mL102.7622 mL
5 mM0.4110 mL2.0552 mL4.1105 mL20.5524 mL
10 mM0.2055 mL1.0276 mL2.0552 mL10.2762 mL
20 mM0.1028 mL0.5138 mL1.0276 mL5.1381 mL
50 mM0.0411 mL0.2055 mL0.4110 mL2.0552 mL
100 mM0.0206 mL0.1028 mL0.2055 mL1.0276 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Dose Conversion

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