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NFAT Inhibitor

Name: NFAT Inhibitor
Brand: TargetMol
SKU: TP1015
Price: 68 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TP1015Cas No. 249537-73-3

Alias VIVIT peptide

NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits the calcineurin-mediated dephosphorylation of NFAT.

NFAT Inhibitor

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Purity: 98.26%

Catalog No. TP1015Alias VIVIT peptideCas No. 249537-73-3

NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits the calcineurin-mediated dephosphorylation of NFAT.

Pack Size	Price	Availability
1 mg	$68	In Stock
5 mg	$263	In Stock
10 mg	$477	In Stock
25 mg	$782	In Stock
50 mg	$1,090	In Stock

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Purity:98.26%

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COA LCMS

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Product Introduction

Bioactivity

Description	NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits the calcineurin-mediated dephosphorylation of NFAT.
Alias	VIVIT peptide

Chemical Properties

Molecular Weight	1683.93
Formula	C₇₅H₁₁₈N₂₀O₂₂S
Cas No.	249537-73-3
Smiles	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)CCSC)C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Relative Density.	1.334 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

H2O: 50 mg/mL (29.69 mM), Sonication is recommended.

DMSO: 10 mM

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	0.5938 mL	2.9692 mL	5.9385 mL	29.6924 mL
5 mM	0.1188 mL	0.5938 mL	1.1877 mL	5.9385 mL
10 mM	0.0594 mL	0.2969 mL	0.5938 mL	2.9692 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.0297 mL	0.1485 mL	0.2969 mL	1.4846 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

inhibitNFAT Inhibitor 1dephosphorylationcell-permeableNFAT-LucNFAT Inhibitor-1InhibitoralcineurinTRAPNFAT InhibitortestosteroneNFATMMP‐9cathepsin-KNFAT Inhibitor1