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Autocamtide-2-related inhibitory peptide

Autocamtide-2-related inhibitory peptide
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Autocamtide-2-related inhibitory peptide

Catalog No. TP2310Cas No. 167114-91-2
Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
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Pack SizePriceAvailabilityQuantity
1 mg$133In Stock
5 mg$302In Stock
10 mg$453In Stock
25 mg$747In Stock
50 mg$1,050In Stock
100 mg$1,420In Stock
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Product Introduction

Bioactivity
Description
Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
In vitro
Autocamtide-2-related inhibitory peptide (a novel synthetic peptide ATP) is a potent inhibitor of CaM-kinase II with an IC50 of 40 nM, which is active in the presence or absence of Ca2+/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93,respectively, under the assay condition used[1].
Chemical Properties
Molecular Weight1497.74
FormulaC64H116N22O19
Cas No.167114-91-2
Storage & Solubility Information
Storagekeep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 10 mM
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.6677 mL3.3384 mL6.6767 mL33.3836 mL
5 mM0.1335 mL0.6677 mL1.3353 mL6.6767 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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