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TargetMol | Compound Library

Autophagy Compound Library

Catalog No. L3200

Autophagy is the natural, regulated mechanism of the cell that disassembles unnecessary or dysfunctional components. Targeted damaged cytoplasmic constituents are isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome. The autophagosome eventually fuses with lysosomes and the contents are degraded and recycled. Autophagy, cellular senescence, and apoptosis are three key responses of a cell facing a stress, correlating with each other. It has been reported that defects of autophagy are associated with genomic damage, metabolic stress, and tumorigenesis. The Autophagy Compound library by TargetMol contains 1248 compounds with defined autophagy-inducing or -inhibitory activity, and is a useful tool for studying the roles of pro- and anti-autophagic molecules in cells as well as for use in in-vitro applications.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L3200

Autophagy Compound Library
sizeIn stock
  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
  • Targets include Autophagy inducers, Autophagy inhibitors, Proteasome, HIF, HDAC, Aurora Kinase, E3 Ligase, mTOR, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

Autophagy
Apoptosis
PI3K
Antibacterial
mTOR
Endogenous Metabolite
Antibiotic
Mitophagy
AMPK
p38 MAPK
HIV Protease
Ferroptosis
Akt
HDAC
NF-κB
Parasite
Reactive Oxygen Species
CXCR
Raf
Calcium Channel
Potassium Channel
VEGFR
Adrenergic Receptor
CDK
Aurora Kinase
COX
Retinoid Receptor
DNA-PK
ERK
EGFR
MEK
p53
DNA/RNA Synthesis
Bcr-Abl
Influenza Virus
P450
FLT
c-Kit
PDGFR
Src
PKC
Topoisomerase
LRRK2
5-HT Receptor
AChR
Antifungal
GSK-3
Virus Protease
CFTR
PKA
CaMK
SARS-CoV
Proteasome
JNK
BCL
FGFR
FXR
E1/E2/E3 Enzyme
FAAH
TNF
HMG-CoA Reductase
S6 Kinase
JAK
Sirtuin
STAT
Sodium Channel
Ras
Microtubule Associated
Dopamine Receptor
Estrogen/progestogen Receptor
PPAR
PDE
HSV
MMP
HIF/HIF Prolyl-Hydroxylase
PERK
Serine/threonin kinase
Caspase
Epigenetic Reader Domain
DUB
TLR
Nrf2
ATM/ATR
c-RET
Mdm2
Dehydrogenase
Mitochondrial Metabolism
TGF-beta/Smad
Casein Kinase
Antioxidant
Phosphatase
PARP
Nucleoside Antimetabolite/Analog
TRP/TRPV Channel
ROCK
HIF
ATPase
Proton pump
Histone Methyltransferase
c-Met/HGFR
Histamine Receptor
Glucocorticoid Receptor
HSP
Trk receptor
IκB/IKK
c-Myc
Estrogen Receptor/ERR
Tyrosine Kinases
MAO
IL Receptor
PTEN
Lipoxygenase
IGF-1R
P-gp
ALK
Beta Amyloid
GABA Receptor
NADPH
Wnt/beta-catenin
Rho
Cysteine Protease
ROS
ribosome
PDK
Phospholipase
HER
NOS
Carbonic Anhydrase
DHFR
HCV Protease
Integrin
DNA Alkylator/Crosslinker
Progesterone Receptor
MRP
Serine Protease
Serotonin Transporter
Glucokinase
Aryl Hydrocarbon Receptor
IAP
Gamma-secretase
Opioid Receptor
DPP-4
Hedgehog/Smoothened
GluR
Prostaglandin Receptor
transporter
Reverse Transcriptase
c-Fms
DNA Methyltransferase
FAK
ROS Kinase
Transferase
Dynamin
Amino Acids and Derivatives
Adenosine Receptor
RAAS
ABC
HBV
Pim
Antifolate
SIK
RIP kinase
P2X Receptor
Molecular Glues
Fatty Acid Synthase
DNA
Androgen Receptor
Ligand for E3 Ligase
PLK
SGK
Cannabinoid Receptor
Monoamine Oxidase
NO Synthase
ROR
Ligands for Target Protein for PROTAC
YAP
BACE
DYRK
Cell wall
Glutathione Peroxidase
GTPase
VDA
iGluR
IRE1
LDL
Drug Metabolite
NMDAR
BTK
Antifection
DNA Alkylation
PGC-1α
CCR
Chk
Norepinephrine
Indoleamine 2,3-Dioxygenase (IDO)
Interleukin
MAPK
AChE
MNK
Antiviral
Histone Acetyltransferase
CRISPR/Cas9
GPR
ATTECs
Syk
NOD
BMI-1
TAM Receptor
Tyrosinase
p97
lysosomal autophagy
AhR
NOD-like Receptor (NLR)
MLK
S1P Receptor
Adenylyl cyclase
CAT
NPC1L1
MyD88
Arginase
LPL Receptor
LTR
Reductase
IFNAR
Arrestin
Na+/Ca2+ Exchanger
RAR/RXR 
Histone Demethylase
Lipase
Tie-2
TOPK
Factor Xa
Melatonin Receptor
Liver X Receptor
Leukotriene Receptor
NAMPT
Glutaminase
FOXO1
IDO
CSF-1R
Myosin
Annexin A
UGT
PAFR
GRK
DNA gyrase
Glucosidase
Hexokinase
Monoamine Transporter
Guanylate cyclase
Smo
PROTAC Linker
Endothelin Receptor
Somatostatin
ACK
Lipid
ATP Citrate Lyase
OXPHOS
BCRP
Beta-Secretase
Survivin
STING
Aminopeptidase
GPCR19
Ephrin Receptor
GluCls
PAI-1
PI4K
Complement System
Gap Junction Protein
Anti-infection
IRAK
Sigma receptor
Thrombin
Imidazoline Receptor
PD-1/PD-L1
Kinesin

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