Atriopeptin II rat, mouse, is an atrial natriuretic peptide that functions as both a diuretic and a natriuretic agent, while also serving as a potent relaxant of vascular smooth muscle [1].

Atriopeptin II rat, mouse (10 nM, 100 min) exhibits vasodilatory effects in isolated rat thoracic aorta, increases cyclic GMP levels, and activates cyclic GMP kinase [1]. Atriopeptin II rat, mouse (0-100 nM) can stimulate testosterone production, with a half-maximal stimulatory concentration of 2.6 nM [2].