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M40 acetate(143896-17-7 free base)
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M40 acetate(143896-17-7 free base)
Catalog No. TP1992L
M40 acetate is a potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat brain in vitro (IC50 = 3 - 15 nM). Attenuates the antidepressant effects of fluoxetine and blocks galanin-induced food intake in vivo. Also exhibits weak partial agonist activity at peripheral GAL2 receptors at doses > 100 nM.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $196 | In Stock | |
| 5 mg | $487 | In Stock | |
| 10 mg | $696 | In Stock | |
| 25 mg | $1,090 | In Stock | |
| 50 mg | $1,490 | In Stock | |
| 100 mg | $1,980 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | M40 acetate is a potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat brain in vitro (IC50 = 3 - 15 nM). Attenuates the antidepressant effects of fluoxetine and blocks galanin-induced food intake in vivo. Also exhibits weak partial agonist activity at peripheral GAL2 receptors at doses > 100 nM. |
| Molecular Weight | 2041.38 |
| Formula | C96H149N23O26 |
| Cas No. |
| Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||
| Solubility Information | DMSO: 10 mM | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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