Shopping Cart
- Remove All
Your shopping cart is currently empty
L 152804
🥰Excellent
Catalog No. T15679Cas No. 6508-43-6
L 152804 is a specific antagonist of the neuropeptide Y Y5 receptor and modulates food intake and energy expenditure thus causing weight loss in diet-induced obese mice.
L 152804
🥰Excellent
Purity: 99.65%
Catalog No. T15679Cas No. 6508-43-6
L 152804 is a specific antagonist of the neuropeptide Y Y5 receptor and modulates food intake and energy expenditure thus causing weight loss in diet-induced obese mice.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $43 | In Stock | |
| 10 mg | $73 | In Stock | |
| 25 mg | $119 | In Stock | |
| 50 mg | $188 | In Stock | |
| 100 mg | $273 | In Stock | |
| 200 mg | $388 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $47 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "L 152804"
DF-1012 FA
DF-1012 FA（163220-65-3 Free base）
T27158LIn house
DF-1012 FA is a structural analog of DF-1012, a neuropeptide inhibitor used in the study of asthma and cough.
- $195
Size
QTY
GW438014A
GW-438014-A, GW 438014 A
T24121469861-49-2
GW438014A is a potent, selective antagonist of the NPY-Y5 receptor, effectively inhibiting food consumption and curbing body weight gain in obese rodents.
- $34
Size
QTY
SF-22
T71749824981-55-7
SF-22 is a neuropeptide Y receptor (Y2R) antagonist that crosses the blood-brain barrier and has potential anti-inflammatory activity for the study of diseases associated with neurological disorders.
- $30
Size
QTY
HT-2157
SNAP-37889, SNAP37889
T5455303149-14-6
HT-2157 (SNAP-37889) is a selective, high-affinity competitive antagonist of the galanin-3 receptor (Gal3), demonstrating effective inhibition of this target.
- $51
Size
QTY
AR-M 1896 Acetate
AR-M 1896 Acetate (367518-31-8 Free base)
T21646L
AR-M 1896 Acetate is the selective agonist of GalR2.
- $565
Size
QTY
JNJ-31020028
JNJ 31020028
T19971094873-14-9
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold selectivity for Y2 versus human Y1/Y4/Y5 receptors.
- $43
Size
QTY
Selvigaltin
GB1211
T637511978336-95-6In house
Selvigaltin (GB1211) is a Gal-3 inhibitor with potential anticancer activity. Selvigaltin is used in the study of cirrhosis and cancer.
- $289
Size
QTY
AC-099 hydrochloride
T83212849335-07-5
AC-099 hydrochloride is a selective full agonist of the neuropeptide FF2 receptor NPFF2R (EC50=1189 nM) and partial agonist function of the neuropeptide FF1 receptor NPFF1R (EC50=2370 nM) that reverses opioid-induced nociceptive sensitization, and may be used to study neurological....
- $40
Size
QTY
Galanin (1-16), mouse, porcine, rat
TP1380125118-77-6
Galanin (1-16), mouse, porcine, rat, is a hippocampal galanin receptor agonist (Kd = 3 nM) exhibiting high biological activity on locus coeruleus neurons.
- $167
Size
QTY
Galantide acetate
Galantide acetate(138579-66-5 Free base)
T15368L
Galantide acetate, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P. Galantide acetate recognizes two classes of galanin binding sites (KD<0.1 nM and ~6 nM) in the rat hypothalamus. Galantide acetate dose dependently (IC50=1.0 nM) antagonizes the galanin-mediated inhibition of the glucose-induced insulin secretion from mouse pancreatic islets. Galantide acetate appears to bind to a single population of SP receptors (KD~40 nM).
- $158
Size
QTY
M617 acetate
TP1993L
M617 acetate is a selective agonist of galanin receptor 1 (GAL1). M617 acetate acts through central GAL1, promotes GLUT4 expression, and enhances GLUT4 content in the cardiac muscle of type 2 diabetic rats. The Ki values are 0.23 and 5.71 nM for GAL1 and GAL2, respectively.
- $285
Size
QTY
AC-263093
T83651849459-86-5
AC-263093 is an NPFFR2 agonist with anxiolytic activity that increases c-Fos protein expression in the paraventricular nucleus of the hypothalamus.
- $40
Size
QTY
Select Batch
Purity:99.65%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | L 152804 is a specific antagonist of the neuropeptide Y Y5 receptor and modulates food intake and energy expenditure thus causing weight loss in diet-induced obese mice. |
| Targets&IC50 | NPY5R:26 nM(ki) |
| In vitro | L 152804 displays Ki of 26 nM for human neuropeptide Y Y5 with > 300-fold selectivity over hY1, hY2, and hY4 receptors[1]. |
| Molecular Weight | 366.45 |
| Formula | C23H26O4 |
| Cas No. | 6508-43-6 |
| Smiles | CC1(C)CC(=O)C(C2C3=C(CC(C)(C)CC3=O)Oc3ccccc23)C(=O)C1 |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 112.5 mg/mL (307.0 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy L 152804 | purchase L 152804 | L 152804 cost | order L 152804 | L 152804 chemical structure | L 152804 in vitro | L 152804 formula | L 152804 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.