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HSDVHK-NH2 acetate

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Catalog No. TP1879L1
Alias P-11 Acetate

P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).

HSDVHK-NH2 acetate

HSDVHK-NH2 acetate

🥰Excellent
Purity: 99.50%
Catalog No. TP1879L1Alias P-11 Acetate
P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).
Pack SizePriceAvailabilityQuantity
1 mg77 €In Stock
5 mg158 €In Stock
10 mg268 €In Stock
25 mg486 €In Stock
50 mg705 €In Stock
100 mg997 €In Stock
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Purity:99.50%
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Product Introduction

Bioactivity
Description
P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).
Targets&IC50
αvβ3 integrin:2.74 nM
In vitro
P11 acetate showed a strong antagonism against avb3-GRGDSP interaction(IC50 = 25.72 nM)[1]. P11 acetate inhibited the HUVEC proliferation due to the induction of HUVEC cell death through caspases activations and its mechanism is related with increased p53 expression[2].P11 acetate significantly inhibited bFGF-induced cell migration compared to the PBS control group[3].
AliasP-11 Acetate
Chemical Properties
Molecular Weight780.39
FormulaC32H52N12O11
SmilesN[C@@H](CC1=CN=CN1)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@H](C(N)=O)CCCCN)=O)CC2=CN=CN2)=O)=O)=O)=O.CC(O)=O
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 7.24 mg/mL (9.28 mM), Sonication is recommended
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2814 mL6.4071 mL12.8141 mL64.0705 mL
5 mM0.2563 mL1.2814 mL2.5628 mL12.8141 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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