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K34c hydrochloride

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Purity:100%

ee:95.11%

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COA LCMS HPLC HNMR CSFC IC

K34c hydrochloride

Catalog No. T41151L

K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.

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Pack Size	Price	Availability
1 mg	$350	In Stock
5 mg	$828	In Stock
10 mg	$1,130	In Stock
25 mg	$1,590	In Stock
50 mg	$1,980	In Stock
100 mg	$2,500	In Stock
500 mg	$4,900	In Stock
1 mL x 10 mM (in DMSO)	$933	In Stock

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Product Introduction

Bioactivity

Description	K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.
In vitro	K34c (20 μM; 24 or 48 h) in combination with 1 μM Ellipticine induces significant apoptosis in U87MG cells.[1] K34c (20 μM; 48 h) significantly decreases Temozolomide-induced senescence in cells transfected with control nontargeting siRNA, without significantly affecting the residual.[1] K34c (20 μM; 24 h) alters the p53 pathway and senescence of cells transfected with siRNA specific for p53.[1]
Alias	K34c hydrochloride(939769-93-4 Free base)

Chemical Properties

Molecular Weight	644.29
Formula	C38H50ClN5O2
Cas No.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 27.5 mg/mL (42.68 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.5521 mL	7.7605 mL	15.5210 mL	77.6048 mL
5 mM	0.3104 mL	1.5521 mL	3.1042 mL	15.5210 mL
10 mM	0.1552 mL	0.7760 mL	1.5521 mL	7.7605 mL
20 mM	0.0776 mL	0.3880 mL	0.7760 mL	3.8802 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

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