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PPI Inhibitor Library

Catalog No. L9400
  Library Compound List   Excel SDF

Protein-protein interaction (PPI) inhibitors represent a vast class of therapeutic targets both intracellularly and extracellularly for a broad range of diseases, for instance cancer and HIV. The human interactome has been estimated to cover ~400,000 protein–protein interactions, making PPIs central to many biological processes, including enzymatic activity, assembly of protein complexes and subcellular localisation. However, PPIs are considered difficult to target. As a part of disease biological processes are often dysregulated, therefore PPIs have become an attractive target for therapy.

TargetMol’s PPI Inhibitor Library, a focused collection of 260 PPI-related compounds, can be used for research on protein-protein interaction.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
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If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
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Product Description

  • A unique collection of 260 PPI-related compounds for drug screening;
  • Targets include PD-1/PD-L1, Bcl-2, BET bromodomain, BRD4 bromodomain, etc.
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC validated to ensure high purity and quality.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L9400)

Library Composition

Epigenetic Reader Domain (47)
BCL (46)
p53 (21)
Ras (14)
Mdm2 (11)
Histamine Receptor (11)
VEGFR (10)
IAP (9)
c-Kit (9)
HCV Protease (8)
HIV Protease (7)
Tyrosine Kinases (6)
EGFR (6)
PDGFR (6)
CDK (5)
PARP (5)
Src (5)
Bcr-Abl (5)
RAAS (5)
Raf (4)
mTOR (4)
ALK (4)
HSP (4)
JAK (3)
Proteasome (3)
Integrin (3)
FLT (3)
PI3K (3)
Dehydrogenase (3)
NF-κB (3)
Thrombin (3)
Caspase (3)
MEK (3)
MMP (2)
Autophagy (2)
ROS (2)
c-Met/HGFR (2)
JNK (2)
AChR (2)
PPAR (2)
COX (2)
TAM Receptor (2)
FGFR (2)
Factor Xa (2)
c-RET (2)
MAPK (2)
PD-1/PD-L1 (2)
Phosphatase (1)
TGF-beta/Smad (1)
PKC (1)
PLK (1)
Potassium Channel (1)
Prostaglandin Receptor (1)
Protease-activated Receptor (1)
P450 (1)
TNF (1)
Retinoid Receptor (1)
ribosome (1)
ROCK (1)
Serine Protease (1)
Sirtuin (1)
STAT (1)
Syk (1)
5-HT Receptor (1)
Integrase (1)
p38 MAPK (1)
DNA/RNA Synthesis (1)
ACK (1)
Adenosine Receptor (1)
Amino Acids and Derivatives (1)
Antibacterial (1)
Antifection (1)
Antiviral (1)
Apoptosis (1)
ATM/ATR (1)
BTK (1)
Carboxypeptidase(CPG2) (1)
CCR (1)
Chk (1)
c-Myc (1)
Cysteine Protease (1)
DNA-PK (1)
Norepinephrine (1)
Dopamine Receptor (1)
DPP-4 (1)
ERK (1)
GABA Receptor (1)
GlyT (1)
HBV (1)
HDAC (1)
Hedgehog/Smoothened (1)
IGF-1R (1)
IL Receptor (1)
Lipoxygenase (1)
MAO (1)
Microtubule Associated (1)
Monoamine Transporter (1)
Wnt/beta-catenin (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE