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TargetMol | Compound Library

PPI Inhibitor Library

Catalog No. L9400

Protein-protein interaction (PPI) inhibitors represent a vast class of therapeutic targets both intracellularly and extracellularly for a broad range of diseases, for instance cancer and HIV. The human interactome has been estimated to cover ~400,000 protein–protein interactions, making PPIs central to many biological processes, including enzymatic activity, assembly of protein complexes and subcellular localisation. However, PPIs are considered difficult to target. As a part of disease biological processes are often dysregulated, therefore PPIs have become an attractive target for therapy. TargetMol’s PPI Inhibitor Library, a focused collection of 485 PPI-related compounds, can be used for research on protein-protein interaction.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9400

PPI Inhibitor Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 485 PPI-related compounds for drug screening;
  • Targets include PD-1/PD-L1, Bcl-2, BET bromodomain, BRD4 bromodomain, etc.
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC validated to ensure high purity and quality.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
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Library Customization | TargetMol Library Composition

Epigenetic Reader Domain
Apoptosis
BCL
p53
Mdm2
Autophagy
HIV Protease
E1/E2/E3 Enzyme
Histone Methyltransferase
Nrf2
PD-1/PD-L1
PROTACs
RIP kinase
IAP
Ferroptosis
Wnt/beta-catenin
Ras
DNA/RNA Synthesis
Histone Acetyltransferase
c-Myc
Rho
CDK
Raf
Sirtuin
NF-κB
Microtubule Associated
Integrin
Caspase
Endogenous Metabolite
Ligands for Target Protein for PROTAC
YAP
Dehydrogenase
PERK
CXCR
COX
PSMA
HSP
Ligand for E3 Ligase
HIF
TNF
Dopamine Receptor
DNA-PK
Src
NEDD8
DNA Alkylator/Crosslinker
IFNAR
GTPase
Phosphatase
GSK-3
PPAR
Parasite
Aryl Hydrocarbon Receptor
iGluR
NMDAR
Integrase
IL Receptor
mTOR
Antibacterial
Carboxypeptidase
Reverse Transcriptase
STAT
Kras
Sodium Channel
HIF/HIF Prolyl-Hydroxylase
Chloride channel
ATPase
Proton pump
NPC1L1
MyD88
p38 MAPK
Estrogen/progestogen Receptor
Antifungal
PI3K
Antioxidant
RAAS
Histamine Receptor
JNK
Glutathione Peroxidase
Mitophagy
Estrogen Receptor/ERR
PARP
Serotonin Transporter
Serine/threonin kinase
Cysteine Protease
Liver X Receptor
Neurotensin Receptor
FXR
Glucokinase
Calcium Channel
PKC
ERK
MAO
Topoisomerase
Myosin
PDE
Gamma-secretase
Mitochondrial Metabolism
Molecular Glues
Reactive Oxygen Species
JAK
CCR
GluR
IGF-1R
DNA
Androgen Receptor
Interleukin
TGF-beta/Smad
Akt
MNK
TLR
SARS-CoV
STING
GPCR19
Ephrin Receptor
transporter
HuR
IκB/IKK
Beta Amyloid
Retinoid Receptor
HDAC
5-HT Receptor
PLK
Potassium Channel
Neurokinin receptor
Discoidin Domain Receptor (DDR)
HMG-CoA Reductase
Tyrosinase
Thrombin
Antibiotic
FAK
AhR
MLK
Monoamine Oxidase