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TargetMol | Compound Library

PPI Inhibitor Library

Catalog No. L9400

Protein-protein interaction (PPI) inhibitors represent a vast class of therapeutic targets both intracellularly and extracellularly for a broad range of diseases, for instance cancer and HIV. The human interactome has been estimated to cover ~400,000 protein–protein interactions, making PPIs central to many biological processes, including enzymatic activity, assembly of protein complexes and subcellular localisation. However, PPIs are considered difficult to target. As a part of disease biological processes are often dysregulated, therefore PPIs have become an attractive target for therapy. TargetMol's PPI Inhibitor Library, a focused collection of 485 PPI-related compounds, can be used for research on protein-protein interaction.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L9400

PPI Inhibitor Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 485 PPI-related compounds for drug screening;
  • Targets include PD-1/PD-L1, Bcl-2, BET bromodomain, BRD4 bromodomain, etc.
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC validated to ensure high purity and quality.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
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Library Customization | TargetMol Library Composition

Epigenetic Reader Domain
Apoptosis
Bcl-2 Family
Autophagy
Nrf2
p53
Mdm2
HIV Protease
E1/E2/E3 Enzyme
Histone Methyltransferase
Caspase
IAP
PD-1/PD-L1
NF-κB
PROTACs
Ferroptosis
Endogenous Metabolite
RIP kinase
Wnt/beta-catenin
DNA/RNA Synthesis
PARP
Histone Acetyltransferase
Ras
p38 MAPK
Microtubule Associated
c-Myc
COX
Sirtuin
STAT
TNF
Parasite
Rho
ERK
Raf
CDK
Antibacterial
Akt
Integrin
Ligands for Target Protein for PROTAC
Dehydrogenase
JNK
IL Receptor
HIF/HIF Prolyl-Hydroxylase
PI3K
PERK
Mitophagy
PPAR
Calcium Channel
PKC
NMDAR
Reactive Oxygen Species
CXCR
mTOR
HSP
Ligand for E3 Ligase
HIF
Sodium Channel
MicroRNA
Dopamine Receptor
DNA-PK
Src
NEDD8
Estrogen/progestogen Receptor
YAP
Antifungal
Antioxidant
DNA Alkylator/Crosslinker
IFNAR
GTPase
Phosphatase
GSK-3
Virus Protease
Aryl Hydrocarbon Receptor
iGluR
PDE
Integrase
JAK
Lipoxygenase
P-gp
Influenza Virus
IκB/IKK
Carboxypeptidase
Reverse Transcriptase
HDAC
GABA Receptor
5-HT Receptor
PLK
Antibiotic
ATPase
Chloride channel
Proton pump
NPC1L1
HCV Protease
MyD88
NADPH
RAAS
Histamine Receptor
Glutathione Peroxidase
Estrogen Receptor/ERR
Serotonin Transporter
Serine/threonin kinase
Cysteine Protease
Liver X Receptor
Neurotensin Receptor
FXR
Glucokinase
VEGFR
MAO
Topoisomerase
Myosin
UGT
Gamma-secretase
Mitochondrial Metabolism
Monoamine Transporter
ROS
Molecular Glues
Smo
Hedgehog/Smoothened
CCR
Cholinesterase (ChE)
MMP
GluR
IGF-1R
Cytochromes P450
DNA
Androgen Receptor
Interleukin
TGF-beta/Smad
MAPK
PSMA
MNK
Prostaglandin Receptor
SARS-CoV
TLR
STING
GPCR19
Ephrin Receptor
transporter
HuR
Beta Amyloid
Retinoid Receptor
PDK
Potassium Channel
ATTECs
Neurokinin receptor
Discoidin Domain Receptor (DDR)
Anti-infection
DNA Methyltransferase
HMG-CoA Reductase
Tyrosinase
Thrombin
FAK
AhR
MLK
NO Synthase
Monoamine Oxidase
Kras