Shopping Cart
- Remove All
Your shopping cart is currently empty
Boc-Asp(OMe)-fluoromethyl ketone
🥰Excellent
Catalog No. T39308Cas No. 187389-53-3
Alias Boc-Asp(OMe)-FMK, Boc-Asp(OMe)-fluoromethyl ketone
Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8.
Boc-Asp(OMe)-fluoromethyl ketone
🥰Excellent
Catalog No. T39308Alias Boc-Asp(OMe)-FMK, Boc-Asp(OMe)-fluoromethyl ketoneCas No. 187389-53-3
Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $40 | In Stock | |
| 5 mg | $97 | In Stock | |
| 10 mg | $155 | In Stock | |
| 25 mg | $313 | In Stock | |
| 50 mg | $493 | In Stock | |
| 100 mg | $723 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $94 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Boc-Asp(OMe)-fluoromethyl ketone"
Tauroursodeoxycholate
Cited
Ursodeoxycholyltaurine, UR 906, TUDCA, Tauroursodeoxycholic Acid, Taurolite
T253214605-22-2
Tauroursodeoxycholate (UR 906), also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. Tauroursodeoxycholate is the more hydrophilic form of ursodeoxycholic acid, which is the more abundant naturally produced bile acid in humans.Tauroursodeoxycholate is being investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis.
- $50
Size
QTY
Cited(Iso)-Z-VAD(OMe)-FMK
T88862634911-81-2
(Iso)-Z-VAD(OMe)-FMK is an isomer of Z-VAD(OMe)-FMK, which is a pan-caspase inhibitor with irreversible properties. Z-VAD(OMe)-FMK is also an inhibitor of ubiquitin C-terminal hydrolase L1 (UCHL1), irreversibly modified by targeting the UCHL1 active site.
Inquiry
Taurochenodeoxycholic Acid Cited
TCDCA, Taurochenodeoxycholate, Chenyltaurine, Chenodeoxycholyltaurine, 12-Deoxycholyltaurine
T2A2481516-35-8
Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.
- $39
Size
QTY
CitedTauroursodeoxycholate sodium Cited
TUDC, Tauroursodeoxycholic acid sodium salt, Sodium Tauroursodeoxycholate (TUDC), Sodium tauroursodeoxycholate
T699335807-85-3
Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.
- $30
Size
QTY
CitedTaurodeoxycholic acid
Taurodeoxychloic acid
T75319516-50-7
Taurodeoxycholic acid (Taurodeoxychloic acid) is a bile acid taurine conjugate of deoxycholic acid, a human metabolite that stabilizes mitochondrial membranes and reduces the formation of free radicals.Taurodeoxycholic acid inhibits apoptosis by blocking calcium-mediated apoptotic pathways and by activation of caspase-12. Taurodeoxycholic acid has neuroprotective activity and has been used to study 3-nitropropionic acid-induced or stabilized hereditary Huntington's chorea (HD).
- $56
Size
QTY
SKLB-163
SKLB163
T261931255099-06-9In house
SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.
- $137
Size
QTY
PAC-1
Procaspase activating compound 1
T2503315183-21-2
PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer, and Thoracic Cancers, among others.
- $43
Size
QTY
Fenbufen
Lederfen, CL-82204
T085936330-85-5
Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by preventing cyclooxygenase from producing prostaglandins which can cause inflammation.
- $38
Size
QTY
Allicin
T3123539-86-6
Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal epithelial cells. Allicin could significantly inhibit vascular smooth muscle cells' proliferation and migration induced by insulin, which may be related to the inhibition of the activation of ERK signal path. Allicin is beneficial in reducing blood cholesterol, triglycerides levels and systolic blood pressure in hypercholesterolemic rats, it may beneficially affect two risk factors for atherosclerosis-hyperlipidemia and hypertension.
- $40
Size
QTY
Allethrin
T25049584-79-2
Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.
- $30
Size
QTY
CIL62
T8468117593-36-9
CIL62 is a Necrostatin-1 dependent inducer of cell death through a caspase-3/7-independent mechanism [1].
- $48
Size
QTY
Crustecdysone
Hydroxyecdysone, Ecdysterone, Commisterone, B-ecdysone, 20-Hydroxyecdysone
T28815289-74-7
Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.
- $60
Size
QTY
Select Batch
Purity:≥98%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8. |
| In vitro | Boc-Asp(OME)-Fluoromethyl Keton (100 μM; 30 minutes; Polymorphonuclear leukocytes) prevents Fas-induced and spontaneous apoptosis (-CH-11)[1], and at 20 μM for 5 hours in J774.1/JA-4 cells, it significantly increases the release of LDH[2]. |
| Alias | Boc-Asp(OMe)-FMK, Boc-Asp(OMe)-fluoromethyl ketone |
| Molecular Weight | 263.26 |
| Formula | C11H18FNO5 |
| Cas No. | 187389-53-3 |
| Smiles | [C@H](NC(OC(C)(C)C)=O)(CC(OC)=O)C(CF)=O |
| Relative Density. | 1.150 g/cm3 at 20℃ |
Storage & Solubility Information
| Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (227.91 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Boc-Asp(OMe)-fluoromethyl ketone | purchase Boc-Asp(OMe)-fluoromethyl ketone | Boc-Asp(OMe)-fluoromethyl ketone cost | order Boc-Asp(OMe)-fluoromethyl ketone | Boc-Asp(OMe)-fluoromethyl ketone chemical structure | Boc-Asp(OMe)-fluoromethyl ketone in vitro | Boc-Asp(OMe)-fluoromethyl ketone formula | Boc-Asp(OMe)-fluoromethyl ketone molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.