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TargetMol | Compound Library

Protease Inhibitor Library

Catalog No. L1100

Protease inhibitors are molecules that inhibit the function of proteases (enzymes that aid the breakdown of proteins), including proteins protease inhibitors, natural protease inhibitors, and synthetic protease inhibitors. (1). Antiprotozoal activity: protease inhibitors could be used against malaria and gastrointestinal protozoal infections; (2). Antiretrovirals: protease inhibitors were the second class of antiretroviral drugs developed widely used to treat HIV/AIDS and hepatitis C; (3). Anticancer activity: Researchers are investigating whether protease inhibitors could possibly be used to treat cancer. For example, nelfinavir and atazanavir are able to kill tumor cells in culture. Inhibitors of the proteasome, such as bortezomib are now front-line drugs for the treatment of multiple myeloma. Marimastat and batimastat are two of the matrix metalloproteinase inhibitors that can be used to treat cancer. The Protease Inhibitor Library by TargetMol, containing 507 small protease and proteasome inhibitors, can be used for research in Chemical Genomics and drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1100

Protease Inhibitor Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 507 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
  • Targets include proteasome, DPP-4, Serine protease, cysteine protease, MMP, Aspartic proteinases, etc;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

MMP
Caspase
Proteasome
Apoptosis
Gamma-secretase
Virus Protease
Cysteine Protease
Serine Protease
Autophagy
SARS-CoV
HIV Protease
DPP-4
Thrombin
Antibacterial
HCV Protease
BCL
Endogenous Metabolite
PARP
NF-κB
p38 MAPK
Parasite
Beta Amyloid
COX
Reactive Oxygen Species
JAK
IL Receptor
Akt
Carboxypeptidase
Protease
P450
TNF
Antibiotic
Antifungal
JNK
Serine/threonin kinase
ERK
Antiviral
PI3K
PPAR
Immunology/Inflammation related
HSV
P-gp
Influenza Virus
Dehydrogenase
Ferroptosis
Antioxidant
Factor Xa
ROS
DUB
DNA/RNA Synthesis
Estrogen/progestogen Receptor
BACE
TRP/TRPV Channel
PKC
CDK
Drug Metabolite
Lipoxygenase
Interleukin
Prostaglandin Receptor
Nrf2
STAT
HDAC
5-HT Receptor
GABA Receptor
HIF/HIF Prolyl-Hydroxylase
NO Synthase
Histamine Receptor
Phosphatase
Mitophagy
Wnt/beta-catenin
Rho
Calcium Channel
IAP
Thrombopoietin Receptor
Epigenetic Reader Domain
mTOR
Beta-Secretase
MAPK
Free radical scavengers
PAI-1
Pyroptosis
ATM/ATR
ribosome
AMPK
Phospholipase
Potassium Channel
AChR
Anti-infection
DNA Methyltransferase
Tyrosinase
NOD-like Receptor (NLR)
p53
ATPase
Proton pump
Carbonic Anhydrase
ROR
Dopamine Receptor
DNA-PK
Src
Dynamin
Amino Acids and Derivatives
gp120/CD4
GSK-3
PKA
Nucleoside Antimetabolite/Analog
Adrenergic Receptor
MAO
E1/E2/E3 Enzyme
UGT
PAFR
NMDAR
BTK
Antifection
Opioid Receptor
Fatty Acid Synthase
Somatostatin
Aurora Kinase
cAMP
IGF-1R
CaMK
DNA
TLR
STING
Aminopeptidase
AIM2
ALK
IκB/IKK
Neprilysin
PI4K
GPR
Complement System
Platelet aggregation
Sodium Channel
Ras
Protease-activated Receptor
FAK
CFTR
S1P Receptor