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TargetMol | Compound Library

Protease Inhibitor Library

Catalog No. L1100

Protease inhibitors are molecules that inhibit the function of proteases (enzymes that aid the breakdown of proteins), including proteins protease inhibitors, natural protease inhibitors, and synthetic protease inhibitors. (1). Antiprotozoal activity: protease inhibitors could be used against malaria and gastrointestinal protozoal infections; (2). Antiretrovirals: protease inhibitors were the second class of antiretroviral drugs developed widely used to treat HIV/AIDS and hepatitis C; (3). Anticancer activity: Researchers are investigating whether protease inhibitors could possibly be used to treat cancer. For example, nelfinavir and atazanavir are able to kill tumor cells in culture. Inhibitors of the proteasome, such as bortezomib are now front-line drugs for the treatment of multiple myeloma. Marimastat and batimastat are two of the matrix metalloproteinase inhibitors that can be used to treat cancer. The Protease Inhibitor Library by TargetMol, containing 343 small protease and proteasome inhibitors, can be used for research in Chemical Genomics and drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1100

Protease Inhibitor Library
sizeIn stock
  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
  • Targets include proteasome, DPP-4, Serine protease, cysteine protease, MMP, Aspartic proteinases, etc;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

MMP
Proteasome
Tyrosinase
Caspase
Apoptosis
Autophagy
HIV Protease
Gamma-secretase
Cysteine Protease
Serine Protease
SARS-CoV
DPP-4
Antibacterial
Thrombin
HCV Protease
Endogenous Metabolite
NF-κB
BCL
p38 MAPK
Parasite
PARP
COX
Beta Amyloid
Serine/threonin kinase
TNF
Virus Protease
PPAR
ERK
Akt
BACE
Glutaminase
P450
Ferroptosis
Antifungal
Factor Xa
VEGFR
Reactive Oxygen Species
Beta-Secretase
P-gp
Influenza Virus
AMPK
GABA Receptor
Antibiotic
Antioxidant
Histamine Receptor
JNK
Mitophagy
HSV
IL Receptor
Lipoxygenase
DUB
Interleukin
Prostaglandin Receptor
transporter
HDAC
AChR
Anti-infection
Estrogen/progestogen Receptor
PI3K
Phosphatase
IAP
Immunology/Inflammation related
CDK
Drug Metabolite
Free radical scavengers
PAI-1
ribosome
5-HT Receptor
Potassium Channel
Platelet aggregation
Sodium Channel
NO Synthase
ATPase
Proton pump
ROR
Src
Amino Acids and Derivatives
Na+/Ca2+ Exchanger
Tyrosine Kinases
Calcium Channel
PKC
Adrenergic Receptor
Topoisomerase
E1/E2/E3 Enzyme
UGT
Glucosidase
PDGFR
JAK
CXCR
Aurora Kinase
IGF-1R
DNA
CaMK
EGFR
MAPK
Antiviral
TLR
Sirtuin
Pyroptosis
ALK
IκB/IKK
STAT
Protease
Phospholipase
c-Kit
Ras
Microtubule Associated
p53
HER

Keywords