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TargetMol | Compound Library

Protease Inhibitor Library

Catalog No. L1100

Protease inhibitors are molecules that inhibit the function of proteases (enzymes that aid the breakdown of proteins), including proteins protease inhibitors, natural protease inhibitors, and synthetic protease inhibitors. (1). Antiprotozoal activity: protease inhibitors could be used against malaria and gastrointestinal protozoal infections; (2). Antiretrovirals: protease inhibitors were the second class of antiretroviral drugs developed widely used to treat HIV/AIDS and hepatitis C; (3). Anticancer activity: Researchers are investigating whether protease inhibitors could possibly be used to treat cancer. For example, nelfinavir and atazanavir are able to kill tumor cells in culture. Inhibitors of the proteasome, such as bortezomib are now front-line drugs for the treatment of multiple myeloma. Marimastat and batimastat are two of the matrix metalloproteinase inhibitors that can be used to treat cancer. The Protease Inhibitor Library by TargetMol, containing 343 small protease and proteasome inhibitors, can be used for research in Chemical Genomics and drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1100

Protease Inhibitor Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
  • Targets include proteasome, DPP-4, Serine protease, cysteine protease, MMP, Aspartic proteinases, etc;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

Proteasome
MMP
Cysteine Protease
Gamma-secretase
SARS-CoV
Serine Protease
DPP-4
Apoptosis
HIV Protease
Caspase
Autophagy
Thrombin
Tyrosinase
HCV Protease
Antibacterial
Beta Amyloid
Serine/threonin kinase
Glutaminase
Ferroptosis
BACE
Factor Xa
Virus Protease
PPAR
Parasite
COX
Beta-Secretase
Histamine Receptor
DUB
transporter
Influenza Virus
Antibiotic
p38 MAPK
Phosphatase
VEGFR
TRP/TRPV Channel
Immunology/Inflammation related
CDK
Drug Metabolite
BCL
P-gp
Prostaglandin Receptor
PAI-1
ribosome
NF-κB
P450
Potassium Channel
ATPase
Proton pump
Src
Amino Acids and Derivatives
Antifungal
Na+/Ca2+ Exchanger
Mitophagy
Tyrosine Kinases
PARP
Calcium Channel
PKC
ERK
IAP
Topoisomerase
PDGFR
IL Receptor
CXCR
Aurora Kinase
IGF-1R
CaMK
DNA
Interleukin
EGFR
Akt
MAPK
Free radical scavengers
ALK
IκB/IKK
Endogenous Metabolite
Protease
HDAC
AMPK
Phospholipase
5-HT Receptor
GABA Receptor
AChR
Platelet aggregation
c-Kit
Sodium Channel
Ras
Microtubule Associated
p53
HER